The Simultaneous Effect of Aerobic Exercise and Matricaria chamomilla L. Flower Extract on the Serum Level of Peptide C in Streptozotocin-Induced Diabetic Rats
{"title":"The Simultaneous Effect of Aerobic Exercise and Matricaria chamomilla L. Flower Extract on the Serum Level of Peptide C in Streptozotocin-Induced Diabetic Rats","authors":"N. Mirazi, S. Bayat, A. H. pour, Z. Izadi","doi":"10.29252/qums.13.9.10","DOIUrl":null,"url":null,"abstract":"Methods: In this experimental study, 24 male Wistar rats (weight range, 200±20g), were randomly divided into 4 groups (n=6): control group (diabetic without treatment and training), MFE (diabetic treated with the extract), aerobic training (diabetic and training), and MFE+aerobic training (diabetic treated with extract+aerobic training). The aerobic training was performed as running on treadmill for 12 weeks (5 days per week, 60min/day, 26meter/min). The rats were diabetized with a single dose of streptozotocin (65mg/kg bw, ip). The MFE groups that daily received 200mg/kg orally (gavaged) along with exercise, were tested for 12 weeks. Data were analyzed using ShapiroWilk test, one way ANOVA, and Tukey post hoc test at the significant level of p<0.05.","PeriodicalId":20865,"journal":{"name":"Qom University of Medical Sciences Journal","volume":"38 1","pages":"10-18"},"PeriodicalIF":0.0000,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Qom University of Medical Sciences Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29252/qums.13.9.10","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Methods: In this experimental study, 24 male Wistar rats (weight range, 200±20g), were randomly divided into 4 groups (n=6): control group (diabetic without treatment and training), MFE (diabetic treated with the extract), aerobic training (diabetic and training), and MFE+aerobic training (diabetic treated with extract+aerobic training). The aerobic training was performed as running on treadmill for 12 weeks (5 days per week, 60min/day, 26meter/min). The rats were diabetized with a single dose of streptozotocin (65mg/kg bw, ip). The MFE groups that daily received 200mg/kg orally (gavaged) along with exercise, were tested for 12 weeks. Data were analyzed using ShapiroWilk test, one way ANOVA, and Tukey post hoc test at the significant level of p<0.05.