MISUSE OF TOPICAL STEROID AN ALARMING PROBLEM IN DERMATOPHYTOSIS

Lokhande Pooja A, Sathe Aparna N
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Abstract

Dermatophytoses, commonly known as ringworm or tinea, represent superficial fungal infections caused by dermatophytes, which are among the most common infections encountered in medicine. Recently, there has been tremendous increase in the incidence of dermatophytosis and also patients don’t respond to the antifungal therapy. Aim - To probe the probable reason for ineffectiveness of subsequent treatment in management of Dadru after pre-use of topical steroid application. Objective - To compare the clinical and mycological cure in participants with or without use of topical steroidal application before participation in clinical trial. Method - An Experimental comparative clinical trial of 6 weeks duration was done in 50 patients with dermatophytic fungal infections, diagnosed clinically with history of using some form of steroidal application. Result - Out of 50 patients 30(60%) patients shown complete cure 20(40%) patients shown ineffectiveness of the treatment, out of 20 patients (75%) patients had history of steroidal use. Conclusion - Misuse of the steroidal formulation in dermatophytic infection may result in ineffectiveness of the treatment.
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滥用局部类固醇是皮肤癣的一个令人担忧的问题
皮肤癣,俗称癣或癣,是由皮肤癣引起的浅表真菌感染,是医学上最常见的感染之一。近年来,皮肤真菌病的发病率急剧上升,而且抗真菌治疗效果不佳。目的:探讨外用类固醇治疗大如后后续治疗无效的可能原因。目的:比较参加临床试验前使用或不使用局部类固醇的临床和真菌学治愈率。方法:对50例皮肤真菌感染患者进行为期6周的对比性临床试验,临床诊断为使用某种形式的类固醇应用史。结果:在50例患者中,30例(60%)患者显示完全治愈,20例(40%)患者显示治疗无效,20例(75%)患者有类固醇使用史。结论-滥用类固醇制剂治疗皮肤真菌感染可能导致治疗无效。
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