EXPLORATION OF HEALING PROMOTING POTENTIALS OF LEAVES OF MORUS ALBA L. IN ALBINO RATS

M. Kaushik, Aditi Kaushik, K. Murti
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引用次数: 5

Abstract

To establish the wound healing activity of aqueous and ethanolic extract of roots of Morus alba. Two models were performed to evaluate the wound healing activity i.e., Incision and Excision model. In incision model the parameter which was carried out was breaking strength of wounded skin. In excision model percentage wound contraction and period of epithelialization was established for both the extracts. Reference standard drug was Aloe vera ointment for comparison with other groups. From the observation in both the models, Aq. extract of Morus alba was found to have greater wound healing activity in terms of breaking strength in incision model and percentage wound contraction, period of epithelialization was highest in excision model compared with other groups. In conclusion, our findings suggest that aq. extract of Morus alba possess better healing ability than the ethanolic extract.
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桑叶对白化病大鼠促愈合作用的探讨
目的:建立桑根水提液和乙醇提液的创面愈合活性。采用切口和切除两种模型评价创面愈合活性。在切口模型中,计算的参数为损伤皮肤的断裂强度。在切除模型中,测定两种提取物的创面收缩率和上皮化时间。对照标准药物为芦荟软膏,与其他组进行比较。从两组模型的观察来看,桑叶提取物在切口模型的破断强度和切除模型的创面收缩率、上皮化时间等方面均较其他组具有更大的创面愈合活性。综上所述,我们的研究结果表明,桑叶提取物比乙醇提取物具有更好的愈合能力。
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