Metastatic basal cell skin cancer with distant metastatic skeletal lesions: a clinical case report

A. Polyakov, A. Buharov, D. A. Miroshnichenko
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Abstract

Clinical cases of distant metastasis of basal cell skin cancer are extremely rarely described in the international publications. This is probably due to the specific locally advanced growth of this histological type of tumor, as well as to the improvement of radical treatment methods for this group of patients. However, despite the development of both diagnostic research methods and treatment tactics, a large number of patients, especially when the primary tumor is located on the face and neck region, choose less effective and not always radical methods of treatment. In turn, non-radical removal of the primary tumor leads not only to difficulties in local control of the disease, but also to lymphogenous, as well as hematogenous spread of tumor cells and the manifestation of systemic metastasis.In the article, we present a clinical case of metastatic basal cell skin carcinoma of the periorbital region with lesions of the bones of the skeleton, namely the thoracic vertebrae manifested 11 years after the detection of the primary tumor.
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转移性基底细胞皮肤癌伴远处转移性骨骼病变:1例临床报告
基底细胞皮肤癌远端转移的临床病例在国际文献中极为罕见。这可能是由于这种组织学类型的肿瘤具有特异性的局部晚期生长,以及针对这组患者的根治性治疗方法的改进。然而,尽管诊断研究方法和治疗策略都有所发展,但大量患者,特别是原发肿瘤位于面部和颈部区域时,选择的治疗方法效果较差,而且并不总是彻底的治疗方法。反过来,非根治性切除原发肿瘤不仅会导致疾病的局部控制困难,而且还会导致肿瘤细胞的淋巴性和血行性扩散,并表现为全身转移。在本文中,我们报告了一例眼眶周围转移性基底细胞皮肤癌的临床病例,在发现原发肿瘤11年后,骨骼即胸椎出现病变。
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