Utilization of Polymeric Nanoparticle in Cancer Treatment: A Review

Abstract

Rapid advancement in medicine and biotechnology has driven the field of drug discovery. Novel approaches of drug delivery such as formulating the polymeric nanoparticles is revolutionizing the future of medicines. Newly potent and target specific drugs led to enhance therapeutic utility. These challenges, coupled with the complexity and variety, are fueling the advancement of novel drug delivery systems that overcome bioavailability and delivery obstacles. In present scenario, nanoparticles have been acting as carriers for delivering a wide range of potential drugs. Due to their versatility and wide range of properties and they represent a promising drug delivery system of controlled and targeted release. The utilization of polymeric nanoparticles is a plan that aims to minimize adverse effect and will optimize therapeutic effects. Nanoparticle-based therapy facilitates safe and efficacious therapy for cancer patients. Advancement in Nanomedicine technologies provides clear evidence that polymeric nanotherapies have a significant impact in oncology. Improvement in therapeutic utility of polymeric nano-particulate system is highlighted in this paper. This review deals with the polymeric nanoparticulate systems, fate of nanoparticles, its types, targetting mechanism, application and recent patents.