Evaluation of mid-term results in our patients treated with N-Butyl cyanoacrylate embolization in saphenous vein insufficiency

A. Kocaoğlu, Cengiz Ovalı
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Abstract

Aim: The aim of this study is to present our mid-term results obtained from patients with advanced saphenous vein insufficiency treated with N-butyl cyanoacrylate embolization (CAE). Material and Methods: In the present study, we included 1013 patients who were treated with CAE because of moderate and severe saphenous vein insufficiency in Eskişehir Osmangazi University Medical Faculty Hospital Cardiovascular Surgery Clinic between January 2015 and November 2019. The patients were rechecked at 1st, 6th, 12th, 24th and 36th months. Venous Clinical Severity Score (VCSS) and Aberdeen Varicose Vein Questionnaire (AVVQ) results recorded at preoperative and postoperativee period. Doppler ultrasonography (USG) was performed to all patients in all controls. The absence of re-canalized flow in Doppler USG was accepted as the success of the procedure. Results: The mean age of 1013 patients was 51.27±14.30 years (448 men (44.2%) and 565 women (55.8%)). The average procedure time was 12.4±2.1 minutes, the average amount of CA used in the procedure was 1.6 ml (min: 1 ml - max: 2ml). In outpatient controls, complication rates was low, thrombophlebitis occurred in 17 patients (1.7%) and ecchymosis occurred in 9 patients (0.9%). The occlusion rate was 97.6% according to the 1-year follow-up results and 93.3% according to the 3-year follow-up results. The decrease in VCSS and AVVQ scores was statistically significant when the preoperative and postoperative period results compared (p<.05). Conclusion: In the present study, we think that CAE is a safely and effective treatment method for saphenous vein insufficiency. It has low complication, high occlusion rates and provides better comfort to the patients.
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应用氰基丙烯酸丁酯栓塞治疗隐静脉功能不全的中期疗效评价
目的:本研究的目的是报告我们对晚期隐静脉功能不全患者采用氰基丙烯酸酯正丁酯栓塞(CAE)治疗的中期结果。材料与方法:在本研究中,我们纳入了2015年1月至2019年11月在eskikiehir Osmangazi大学医学院附属医院心血管外科诊所因中重度隐静脉功能不全而接受CAE治疗的1013例患者。于第1、6、12、24、36个月复查。术前、术后分别记录静脉临床严重程度评分(VCSS)和阿伯丁静脉曲张问卷(AVVQ)。所有患者均行多普勒超声检查(USG)。在多普勒USG中没有再通流被认为是手术的成功。结果:1013例患者平均年龄51.27±14.30岁,其中男性448例(44.2%),女性565例(55.8%)。平均手术时间为12.4±2.1分钟,平均CA用量为1.6 ml(最小为1 ml -最大为2ml)。在门诊对照组中,并发症发生率较低,17例(1.7%)患者发生血栓性静脉炎,9例(0.9%)患者发生瘀斑。1年随访时闭塞率为97.6%,3年随访时闭塞率为93.3%。术前、术后VCSS、AVVQ评分比较,差异有统计学意义(p< 0.05)。结论:CAE是一种安全有效的治疗隐静脉功能不全的方法。并发症少,闭塞率高,患者舒适度好。
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