GEANT4 Study of Proton–Body Interactions

J. A. López, S. González, O. Rodriguez, J. Holmes, R. Alarcon
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引用次数: 1

Abstract

Received: September 18, 2020 Accepted: January 09, 2021 Published Online: February 10, 2021 Proton therapy uses a beam of protons to destroy cancer cells. A problem of the method is the determination of what part of the body the protons are hitting during the irradiation. In a previous study we determine that by capturing the gamma rays produced during the irradiation one can determine the location of the proton-body interaction, in this work we investigate if by examining the gamma rays produced it is possible to determine the body part that produced the gamma rays by the proton collision. This study uses GEANT4 computer simulations of interactions of proton-tissue, protonbrain, proton-bone, etc., which produce gamma rays, to determine the characteristics of the gamma rays produced. We then analyze the characteristics of the gamma rays to find signatures that could be used to determine the source of the rays. In particular, we study the distribution of gamma ray energies, their full-width half-maximum, energy resolution, maximum height, and total number of counts. This study concludes that it is possible to use the gamma ray spectra to determine what body part produced it.
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质子-体相互作用的研究
收稿日期:2020年9月18日收稿日期:2021年1月09日发表在线日期:2021年2月10日质子治疗使用一束质子来破坏癌细胞。该方法的一个问题是确定在辐照过程中质子击中了人体的哪个部位。在之前的一项研究中,我们确定通过捕获在辐照过程中产生的伽马射线可以确定质子-体相互作用的位置,在这项工作中,我们研究是否可以通过检查产生的伽马射线来确定由质子碰撞产生伽马射线的身体部位。本研究利用GEANT4计算机模拟质子-组织、质子-脑、质子-骨等产生伽马射线的相互作用,确定产生的伽马射线的特性。然后我们分析伽马射线的特征,找到可以用来确定射线来源的特征。特别地,我们研究了伽马射线能量的分布,它们的全宽度半最大值,能量分辨率,最大高度和总计数。这项研究的结论是,有可能使用伽马射线光谱来确定产生它的身体部位。
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