Ya‐Ching Shen, Kuang-Liang Lo, Y. Kuo, R. Chakraborty
{"title":"Polycyclic Quinones and Hydroquinones, Antitumor Constituents from Taiwanese Marine Sponge Xestospongia Sp","authors":"Ya‐Ching Shen, Kuang-Liang Lo, Y. Kuo, R. Chakraborty","doi":"10.7019/CPJ.200206.0207","DOIUrl":null,"url":null,"abstract":"Eight polycyclic quinines and hydroquinones were isolated from marine sponge Xestospongia spp. They are halenaquinone (1), halenaquinol (2), 14-methoxyxestoquinone (3), 15-methoxyxes-toquinone(4), xestoquinone (5), 15-chloro-14-hydroxyxestoquinone (6), adociaquinone A (7) and adociaquinone B (8). Biological screening revealed that compounds 7 and 8 possessed in vitro cytotoxicity against KB 16 and HEP-3B tumor cell lines.","PeriodicalId":22409,"journal":{"name":"The Chinese Pharmaceutical Journal","volume":"39 1","pages":"207-213"},"PeriodicalIF":0.0000,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Chinese Pharmaceutical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7019/CPJ.200206.0207","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Eight polycyclic quinines and hydroquinones were isolated from marine sponge Xestospongia spp. They are halenaquinone (1), halenaquinol (2), 14-methoxyxestoquinone (3), 15-methoxyxes-toquinone(4), xestoquinone (5), 15-chloro-14-hydroxyxestoquinone (6), adociaquinone A (7) and adociaquinone B (8). Biological screening revealed that compounds 7 and 8 possessed in vitro cytotoxicity against KB 16 and HEP-3B tumor cell lines.
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