Cyto-toxicity and oligodynamic effect of bio-synthesized silver nanoparticles from plant residue of Artocarpus altilis and its spectroscopic analysis

V. Nayagam, K. Palanisamy, Dons Thiraviadoss
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Abstract

The medicinal plant residue obtained to synthesis AgNPs is the thrust area of research today. The present research work emphasis on the AgNPs synthesized from a medicinal plant residue Artocarpus altilis whose secondary metabolites bear responsible for the confined size of the AgNPs. Further, the AgNPs were analyzed for Physico-chemical analysis, where FT-IR Peak value gives the functional groups of A. altilis. FESEM analyses show surface morphology with 44 nm. EDAX analyses of show metal precursor involved in the process. XRD patterns show the crystalline structure. The AgNPs was analysised for the antibacterial assay against five human pathogens. Finally, cyto-toxic activity of AgNPs was analyzed with two human cancer cell lines namely MCF 7 lung cancer cell line and A549 breast cancer cell line. Hence, the novel and eco-friendly AgNPs are safe with its biocompatibility which becomes a promising agent in the biomedical precisely.
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山茱萸植物残渣合成纳米银的细胞毒性和寡动力学效应及其光谱分析
利用药用植物残渣合成AgNPs是目前研究的热点。目前的研究重点是利用药用植物残基山茱萸合成AgNPs,其次生代谢物与AgNPs的大小有关。此外,对AgNPs进行了理化分析,其中FT-IR峰值给出了山茱草的官能团。FESEM分析显示表面形貌为44 nm。EDAX分析显示了该过程中涉及的金属前驱体。XRD图显示了晶体结构。AgNPs对5种人致病菌进行抑菌试验。最后,用mcf7肺癌细胞系和A549乳腺癌细胞系对AgNPs的细胞毒活性进行了分析。因此,新型生态友好的AgNPs具有良好的生物相容性和安全性,在生物医学领域具有广阔的应用前景。
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