Aspectos clínicamente relevantes para pacientes diabéticos en tratamiento con insulina: prevención de hipoglucemias y flexibilidad en la administración

Abstract

Two aspects particularly relevant for people with diabetes treated with insulin are prevention of hypoglycemia and flexibility in its administration. Both aspects have an important impact in the achievement of blood glucose targets and in the patient quality of life. In the last few years, advances in insulin therapy, with rapid-acting and long-acting insulin analogs, have contributed to reducing the risk of hypoglycemia. Degludec, a new long-acting basal insulin analogue, seems to reduce even more and consistently the risk of nocturnal hypoglycemia, which are particularly inconvenient as they interfere with sleep quality and duration. In addition, due to its duration of action over 42 hours, it may allow higher injection flexibility without compromising glycemic control and safety.