Effects of silver nanoparticle/graphene oxide composite on the properties of polymethyl methacrylate base material in vitro

IF 2.9 4区材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Materials Technology Pub Date : 2023-05-27 DOI:10.1080/10667857.2023.2214025

Siqi Tang, Xu Gao, Huanhuan Guo, Yanjin Guan, Meng Lin, Zheng Zheng

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Abstract

ABSTRACT Polymethyl methacrylate (PMMA) has been widely used in stomatology to prepare denture bases. However, issues such as a porous structure and high water absorption rate facilitate bacterial growth. This study aimed to synthesize silver nanoparticle/graphene oxide (AgNPs/GO) composites by the chemical reduction method, which was mixed with PMMA by the ball milling method to improve the antibacterial properties of PMMA. Scanning electron microscopy and transmission electron microscopy showed that AgNPs were uniformly dispersed on the GO sheets. AgNPs/GO composite and GO were investigated using x-ray diffraction. The modified AgNPs/GO/PMMA composite demonstrated enhanced antibacterial properties against Streptococcus mutans based on the film adhesion test. Also, the number of bacteria decreased and the morphology of bacteria changed with the increase in mass fraction. Besides, the improved mechanical properties were confirmed by the friction and contact angle tests. Moreover, the composite did not induce cytotoxicity in human gingival mesenchymal stem cells.

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来源期刊

Materials Technology 工程技术-材料科学：综合

CiteScore

6.00

自引率

9.70%

发文量

105

审稿时长

8.7 months

期刊介绍： Materials Technology: Advanced Performance Materials provides an international medium for the communication of progress in the field of functional materials (advanced materials in which composition, structure and surface are functionalised to confer specific, applications-oriented properties). The focus is on materials for biomedical, electronic, photonic and energy applications. Contributions should address the physical, chemical, or engineering sciences that underpin the design and application of these materials. The scientific and engineering aspects may include processing and structural characterisation from the micro- to nanoscale to achieve specific functionality.