POLYMORPHISM OF COLLECTION, TRANSFUSION AND EFFECTIVENESS OF DONOR PLATELETS CONCENTRATES.

M. Gubanova, R. Ayupova, E. Zhiburt
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引用次数: 2

Abstract

There were compared the results of 520 platelets transfusions in 8 centers. In the surveyed organizations part of prophylactic platelet transfusions ranged from 10% to 91%. On average platelet transfusions for the prevention of bleeding in 3,6 times more often than to stop the bleeding. 67,5% ofrecipients ofplatelets have oncology diseases. Target platelet concentrations for preventive transfusions seems high compared to modern evidence-based value - 10 @. 10⁰/l. 25% ofprophylactic transfusions included in the study were performed in patients with platelet count of 30 @. 10⁰l or more. In 76,7% of transfusions used platelet concentrates prepared by apheresis. Single whole blood- derived-units are used at 3,7 times more often than pooled platelets.
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供体浓缩血小板采集、输注及有效性的多态性。
比较了8个中心520例血小板输注的结果。在被调查的组织中,预防性血小板输注的比例从10%到91%不等。平均输血小板用于预防出血的次数为止血的3、6倍。67.5%的血小板接受者患有肿瘤疾病。预防性输血的目标血小板浓度似乎高于现代循证值- 10 @。10⁰/ l。研究中25%的预防性输血是在血小板计数为30 @的患者中进行的。10⁰1或更多。在76.7%的输注中,使用了单采制备的血小板浓缩物。单个全血源性血小板的使用频率是合并血小板的3.7倍。
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