Large-Scale Beard Extraction Enhances the Cosmetic Results of Scalp Hair Restoration in Advanced Androgenetic Alopecia in East Asian Men: A Retrospective Study.

IF 1.2 4区 化学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of Carbohydrate Chemistry Pub Date : 2020-02-01 Epub Date: 2019-11-29 DOI:10.1007/s13555-019-00344-z
De-Cong Zhu, Ye He, Zhe-Xiang Fan, Jin Wang, Qian Qu, Zhi-Qi Hu, Yong Miao
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Abstract

Introduction: Beard hair serves as an important additional donor supply to support hair transplantation in hirsute patients with extensive alopecia and lacking sufficient occipital hair. However, the efficacy and safety of large-scale beard hair extraction have not been studied extensively in the East Asian population.

Methods: Data obtained from hirsute patients with extensive alopecia who underwent hair transplantation between March 2017 and December 2018 at Nanfang Hospital were analyzed. Occipital and beard hair were evaluated separately during the pre-, intra-, and post-operative periods. Individual beard hair follicular units (FUs) were harvested under tumescence using a hollow punch with an outer diameter of 0.8-0.9 mm. Follow-up examinations were scheduled at 3-5 days, 1 month, and 9 months postoperatively to check for complications, determine the survival rate of mixed, transplanted FU grafts, and assess patient satisfaction. Data were collected and analyzed statistically.

Results: A total of 36 hirsute, male patients with advanced androgenetic alopecia (AGA) (Norwood-Hamilton V-VI) were included in this study. The density of the occipital and beard areas was 78.6 ± 4.6 and 48.4 ± 9.3 FU, respectively. It took 3.1 ± 0.9 h to harvest 3135 ± 863 FUs from the occipital area and 2.1 ± 0.6 h to harvest 2352 ± 599 FUs from the beard area. The transection rate for occipital FUs and beard FUs was 3.7 ± 0.4 and 3.9 ± 0.2%, respectively. Completion of the operation took approximately 10.0 ± 0.9 h, and no serious complications were reported 5 days after the procedure. An FU survival rate of 95.7 ± 1.6% was observed at 9 months after transplantation, with no visible hypopigmented scars observed in the bare areas. All patients were satisfied with the resulting cosmetic appearance.

Conclusion: Large-scale beard extraction, when combined with occipital hair extraction, is a safe and effective treatment to enhance the cosmetic appearance of East Asian men with advanced AGA.

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大规模剔除胡须可提高东亚男性晚期雄激素性脱发患者头皮毛发修复的美容效果:一项回顾性研究。
导言:胡须毛发是多毛患者大面积脱发和枕部毛发不足时进行毛发移植的重要补充供体。然而,在东亚人群中,大规模提取胡须毛发的有效性和安全性尚未得到广泛研究:分析了2017年3月至2018年12月期间在南方医院接受毛发移植手术的多毛广泛脱发患者的数据。在术前、术中和术后分别对枕部毛发和胡须毛发进行评估。使用外径为 0.8-0.9 毫米的空心打孔器,在膨化条件下提取单个胡须毛囊单位(FU)。在术后 3-5 天、1 个月和 9 个月进行随访检查,以检查并发症,确定混合移植的 FU 移植物的存活率,并评估患者的满意度。收集数据并进行统计分析:本研究共纳入了 36 名多毛的男性晚期雄激素性脱发(AGA)患者(诺伍德-汉密尔顿 V-VI)。枕部和胡须部位的密度分别为 78.6 ± 4.6 FU 和 48.4 ± 9.3 FU。从枕部采集3135±863个FU需要3.1±0.9小时,从胡须部采集2352±599个FU需要2.1±0.6小时。枕部 FU 和胡须 FU 的横切率分别为 3.7 ± 0.4% 和 3.9 ± 0.2%。手术完成时间约为 10.0 ± 0.9 小时,术后 5 天未报告严重并发症。移植后 9 个月,FU 存活率为 95.7 ± 1.6%,裸露区域未发现明显的色素沉着疤痕。所有患者都对手术后的外观效果表示满意:结论:大面积胡须提取与枕部毛发提取相结合,是一种安全有效的治疗方法,可改善东亚男性晚期 AGA 患者的外观。
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来源期刊
Journal of Carbohydrate Chemistry
Journal of Carbohydrate Chemistry 化学-生化与分子生物学
CiteScore
2.10
自引率
0.00%
发文量
20
审稿时长
1 months
期刊介绍: The Journal of Carbohydrate Chemistry serves as an international forum for research advances involving the chemistry and biology of carbohydrates. The following aspects are considered to fall within the scope of this journal: -novel synthetic methods involving carbohydrates, oligosaccharides, and glycoconjugates- the use of chemical methods to address aspects of glycobiology- spectroscopic and crystallographic structure studies of carbohydrates- computational and molecular modeling studies- physicochemical studies involving carbohydrates and the chemistry and biochemistry of carbohydrate polymers.
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