Comparison of the effect of chamomile and chlorhexidine glucosan cleansing on dental plaque and mucosal lesions of ventilated patients in the intensive care unit

Fatemeh Sabzehkar, M. Mogharab, Gholamreza Sharifzadeh, Zahra Kiani
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Abstract

Background and Aims: The use of methods with minimal complications and risk is of utmost importance in the promotion of oral hygiene in the care of intensive care unit (ICU) patients. The present study aimed to compare the effect of chamomile mouthwash and chlorhexidine gluconate on dental plaque and oral mucosal lesions of patients under ventilator in the intensive care unit. Materials and Methods: This randomized controlled clinical trial was conducted on 50 eligible patients who were selected via available sampling method from among trauma patients in the ICU of Imam Reza (AS) Hospital in Birjand. They were assigned to two groups of chamomile extract 10% (n=25) and chlorhexidine gluconate 0.2% (n=25) by block randomization. In each group, the solution was used three times a day every 8 hours for 5 days. The instruments were the Backas Assessment Checklist (BOAS) and the Mucosal Plate (MPS). Results: In both groups, the mean total score of oral mucosal lesions and dental plaque significantly decreased 2 and 5 days after the intervention, compared to the pre-intervention (P<0.001); nonetheless, the two groups were not significantly different in this regard (P>0.05). Furthermore, there was no statistically significant difference in the mean changes in the total scores of oral mucosal lesions and dental plaque at different times in the two groups (P>0.05). Conclusion: Chamomile mouthwash and chlorhexidine mouthwash have similar beneficial effects on dental plaque and oral mucosal lesions of ventilated patients admitted to the ICU.
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洋甘菊与氯己定葡聚糖清洗对重症监护病房通气患者牙菌斑及黏膜病变的影响比较
背景和目的:在重症监护病房(ICU)患者的口腔卫生护理中,使用并发症和风险最小的方法是至关重要的。本研究旨在比较洋甘菊漱口水和葡萄糖酸氯己定对重症监护病房呼吸机下患者牙菌斑和口腔黏膜病变的影响。材料与方法:本随机对照临床试验从Birjand伊玛目礼萨(AS)医院ICU外伤患者中通过现有抽样方法选出50例符合条件的患者。采用分组随机法将患者分为洋甘菊提取物10%组(n=25)和葡萄糖酸氯己定0.2%组(n=25)。每组每天使用3次,每8小时一次,连续使用5天。仪器为Backas评估检查表(BOAS)和粘膜板(MPS)。结果:干预后2、5 d,两组患者口腔黏膜病变和牙菌斑平均总分均较干预前显著降低(P0.05)。两组患者口腔黏膜病变及牙菌斑总分在不同时间的平均变化比较,差异均无统计学意义(P < 0.05)。结论:洋甘菊漱口水与氯己定漱口水对ICU通气患者牙菌斑及口腔黏膜病变的有益作用相似。
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