Long-term results of bare metal stents and frozen elephant trunk prosthesis using in aortic dissection surgery

D. Sirota, M. Zhulkov, D. Khvan, A. G. Makaev, A. Fomichev, H. Agaeva, A. Sabetov, B. Kozlov, A. Chernyavskiy
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Abstract

Aim. Comparative assessment of long-term results of bare metal stents and frozen elephant trunk prosthesis using in aortic dissection I DeBakey type.Methods. The retrospective comparative evaluation of different surgery results (2001–2017) in 213 patients with DeBakey type I aortic dissection was performed. Patients was divided in to 3 groups: Group 1 — standard treatment (hemiarch or total arch replacement) (n = 121), Group 2 — arch reconstruction with bare metal stent (n = 55), Group 3 — arch reconstruction with frozen elephant trunk prosthesis (n = 37). For groups equation we used propensity score matching analysis (PSM).Results. A pairwise comparison with the formation of three groups equated by the PSM method was performed. Long-term mortality in PSM 1 was 88 [82; 96] % (Group 1) и 89 [79; 100] % — (Group 2) respectively (p = 0.893). Long-term mortality in PSM 2 was 85 [71; 100] % in Group 1 and 94 [84; 100] % — Group 3 respectively (p = 0.342). Long-term mortality in PSM 3 was 88 [77; 100] % in Group 2 и 80 [64; 100] % — Group 3 respectively (p = 0.457). Freedom from aortic and mortality events (surrogate end point) in PSM 1 was 68% and 75% (p>0.999), PSM 2 was 50% and 100% (p = 0.006), PSM 3 was 73% and 89% (p = 0.22).Conclusion. There were no any statistical differences in long-term mortality and in surrogate end point (aortic events and mortality) between groups, but there was a trend to better results in Group 3.
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金属支架和冷冻象鼻假体在主动脉夹层手术中的远期效果
的目标。裸金属支架与冷冻象鼻假体在主动脉夹层中的远期疗效比较对213例DeBakey I型主动脉夹层患者2001-2017年不同手术效果进行回顾性比较评价。患者分为3组:第1组-标准治疗(全弓或全弓置换)(n = 121),第2组-裸金属支架重建弓(n = 55),第3组-冷冻象鼻修复弓(n = 37)。对于群体方程,我们使用倾向得分匹配分析(PSM)。两两比较,形成三个组等价的PSM方法进行。PSM 1的长期死亡率为88 [82;96 %(第一组)89 [79;[100] % -(第二组),差异有统计学意义(p = 0.893)。PSM 2的长期死亡率为85 [71];1组100 %,94组84 %;[100] % - 3组(p = 0.342)。PSM 3的长期死亡率为88 [77;2组100 %,80例[64;[100] % - 3组(p = 0.457)。PSM 1组主动脉事件无发生率和死亡事件发生率(替代终点)分别为68%和75% (p>0.999), PSM 2组为50%和100% (p = 0.006), PSM 3组为73%和89% (p = 0.22)。两组之间的长期死亡率和替代终点(主动脉事件和死亡率)没有统计学差异,但第3组有更好的结果趋势。
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来源期刊
Patologiya krovoobrashcheniya i kardiokhirurgiya
Patologiya krovoobrashcheniya i kardiokhirurgiya Medicine-Cardiology and Cardiovascular Medicine
CiteScore
1.00
自引率
0.00%
发文量
42
审稿时长
12 weeks
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