Peripheral and central pathophysiological changes in a new rat model of acid reflux combined with mental stress

Ting-ting Xu, Li Li, Lin Geng, Bingduo Zhou, Shengliang Zhu
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Abstract

Mental stress is an important risk factor for gastroesophageal reflux disease (GERD), which interacts with acid reflux and affects the efficacy of single acid suppression treatment. However, the specific mechanism remains elusive, and there is a lack of available models for further support.
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胃酸反流合并精神应激新模型大鼠外周和中枢病理生理变化
精神压力是胃食管反流病(GERD)的重要危险因素,与胃酸反流相互作用,影响单次抑酸治疗的效果。然而,具体的机制仍然难以捉摸,并且缺乏可用的模型来进一步支持。
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