{"title":"OPTIMIZATION OF CHEMOTHERAPY OF MALIGNANT TUMORS BASED ON DELIVERY OF DRUGS WITH ENHANCED CONVECTION","authors":"O. B. Stelya, D. Klyushin","doi":"10.17721/2706-9699.2022.1.06","DOIUrl":null,"url":null,"abstract":"The article describes a numerical method for optimizing the chemotherapy of malignant tumors on the basis of drug delivery using increased convection. The problem of optimal control with point sources for reaching the desired intratumor distribution of drugs in macroscopic scale granting the properties of intersticial space and effects of convective diffusion is considered. The efficiency of proposed algorithm for optimal control is shown.","PeriodicalId":40347,"journal":{"name":"Journal of Numerical and Applied Mathematics","volume":"21 1","pages":""},"PeriodicalIF":0.1000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Numerical and Applied Mathematics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17721/2706-9699.2022.1.06","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The article describes a numerical method for optimizing the chemotherapy of malignant tumors on the basis of drug delivery using increased convection. The problem of optimal control with point sources for reaching the desired intratumor distribution of drugs in macroscopic scale granting the properties of intersticial space and effects of convective diffusion is considered. The efficiency of proposed algorithm for optimal control is shown.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
