Ophthalmic Drug Delivery System-A Concise Review on its Conventional and Novel Approaches

Abstract

The main aim of this review is to focus on the various kinds of approaches which are used in ophthalmic drug delivery. Ophthalmic drug delivery system is used to treat various conditions associated with eye. The main purpose of a formulation designer is to formulate an eye formulation which could reside in the eye in an optimum concentration and for a proper duration for its proper effect. The main problem seen in the conventional dosage forms is their poor bioavailability due to fast precorneal drug loss primarily due to nasolacrimal drainage. The residence time of conventional formulations is also very less in the eye resulting into minimal advantages. In order to combat all these problems, now days the pharmaceutical scientists are very much involved in the research towards the novel approaches of ophthalmic drug delivery. The present paper enlists the important novel formulations which have been developed recently and explore their various advantages over conventional forms.