José Eduardo Ribeiro Honório Júnior, Jéssica Rodrigues de Moraes Barriga, Dara da Silva Mesquita, J. Pinto
{"title":"Anxiolytic and antidepressant effects of cannabidiol: a systematic review","authors":"José Eduardo Ribeiro Honório Júnior, Jéssica Rodrigues de Moraes Barriga, Dara da Silva Mesquita, J. Pinto","doi":"10.12662/2317-3076JHBS.V9I1.3366.P1-7.2021","DOIUrl":null,"url":null,"abstract":"Objetctive: Realize a systematic review on articles about cannabidiol (CBD) as an anxiolytic and antidepressant drug. Methodology: A systematic review in PubMed, Science Direct and PsycINFO databases taking into consideration articles published in English and Portuguese from 2008 to 2018 with animal experimentation. Results: Eleven articles with experimental studies on animals were included. All studies exhibited anxiolytic and antidepressant activities after CBD use. Conclusion: It was proven by several experiments the anxiolytic and antidepressant activity of CBD, however there is still a need of more preclinicals and clinicals studies to elucidate its mechanisms.","PeriodicalId":16071,"journal":{"name":"Journal of Health & Biological Sciences","volume":"37 1","pages":"1"},"PeriodicalIF":0.0000,"publicationDate":"2021-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Health & Biological Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12662/2317-3076JHBS.V9I1.3366.P1-7.2021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objetctive: Realize a systematic review on articles about cannabidiol (CBD) as an anxiolytic and antidepressant drug. Methodology: A systematic review in PubMed, Science Direct and PsycINFO databases taking into consideration articles published in English and Portuguese from 2008 to 2018 with animal experimentation. Results: Eleven articles with experimental studies on animals were included. All studies exhibited anxiolytic and antidepressant activities after CBD use. Conclusion: It was proven by several experiments the anxiolytic and antidepressant activity of CBD, however there is still a need of more preclinicals and clinicals studies to elucidate its mechanisms.
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