Testicular adrenal rest cells in congenital adrenal hyperplasia

Q4 Medicine Journal of Clinical and Translational Endocrinology: Case Reports Pub Date : 2021-12-01 DOI:10.1016/j.jecr.2021.100103

Adnan Haider MD , Oksana Symczyk MD , Alexandra Hardy MD , Anusha Kothapalli MD

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引用次数: 0

Abstract

We present a case of untreated Congenital adrenal hyperplasia presenting with bilateral giant Adrenal myelolipoma and Testicular adrenal rest cells.

Methods

We discuss clinical presentation diagnostic evaluation and subsequent management and follow up of CAH with TART's.

Results

Our patient was not adherent to Glucorticoid and mineralocorticoid treatments between age 18 to 47 and presented with back pain most likely resulting from Bilateral giant adrenal myelolipoma. Interestingly he did not require any stress steroids during this time. His adrenal myelolipoma progressively increased in size. Comparison CT is available from 2004 to 2020. Testicular adrenal rest cells and possibly infertility also resulted from uncontrolled CAH for a long period of time.

Conclusion

This case demonstrates the significance of CAH treatment compliance and highlights sequela and management of untreated CAH.

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先天性肾上腺增生的睾丸肾上腺休息细胞

摘要我们报告一例未经治疗的先天性肾上腺增生，表现为双侧巨大肾上腺骨髓瘤及睾丸肾上腺休息细胞。方法对CAH合并TART的临床表现、诊断、评价及后续处理及随访进行探讨。结果该患者在18至47岁期间未坚持糖皮质激素和矿皮质激素治疗，并表现出背部疼痛，很可能是双侧巨大肾上腺骨髓瘤所致。有趣的是，在这段时间里，他没有需要任何应激类固醇。他的肾上腺骨髓瘤逐渐增大。对比CT从2004年到2020年可用。长时间不受控制的CAH也可导致睾丸肾上腺休息细胞和可能的不育。结论本病例说明了CAH治疗依从性的重要性，并强调了未经治疗的CAH的后遗症和处理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical and Translational Endocrinology: Case Reports Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

1.10

自引率

0.00%

发文量

审稿时长

27 weeks

期刊介绍： The journal publishes case reports in a variety of disciplines in endocrinology, including diabetes, metabolic bone disease and osteoporosis, thyroid disease, pituitary and lipid disorders. Journal of Clinical & Translational Endocrinology Case Reports is an open access publication.