A Case of Multiple Eccrine Poromas with a History of Chemotherapy and Allogeneic Peripheral Blood Stem Cell Transplantation.

Abstract

A "poroid cell neoplasm" is a general term used to describe nodular tumors that consist of poroid cells and cuticular cells. Eccrine poroma, the most common type of poroid cell neolplasm, is a tumor continuous with the epidermis and extends into the dermis in a cord-like fashion. This tumor is almost always seen as a single lesion, with cases of multiple eccrine poromas (eccrine poromatosis) being exceedingly rare. In fact, there have only been about 20 reported cases of multiple eccrine poromas worldwide; all of which were associated with some immunosuppressive state. Here we report another case of eccrine poromatosis; this time in a patient who received an allogeneic peripheral blood stem cell transplant for acute lymphocytic leukemia 18 years prior. Our case of eccrine pormatosis is particularly rare that it involved a truncal tumor distribution, whereas the other reported cases were generally isolated to the extremities.