Evaluation of Biomedical Activity of ZnO Coated Bionanocomposites Film

Abstract

Bionanocomposites materials are the ideal alternative for petroleum-based products. They solve not only the global warming issue but also the problems of multidrug-resistant pathogens. We have synthesized a biopolymer-based ZnO nanocomposites film by using cellulose as supporting agent and the extract of Livistona jekinsiana as reducing agents. We also utilized the antibacterial property of chitosan and superior delivery property of -cyclodextrin in the synthesis of bionanocomposites. The new and novel cellulose/chitosan/-cyclodextrin/ Livistona jekinsiana/ZnO bionanocomposites film (CCCLZF) as a promising biomedical applicant was utilized for the first time. Several characteristics were performed to confirm the shape, size, structure, chemical composition, morphology, thermal properties, stability of the films, they are UV-Visible spectroscopy, FTIR spectroscopy, XRD pattern, SEM, and TEM images, EDS, TGA, DTA, DLS, and Zeta potential. To study the biomedical property of the CCCLZF; the antimicrobial, antioxidant, and anti-inflammatory activity of the film was examined. Drug delivery of the film was also investigated. All the experiments obtained good purposeful results. Therefore, CCCLZF will be a promising material in the pharmaceutical and food packaging industry