A detailed quality control assessment of polyherbal pain reliever cream

S. Joshi, Khushboo Vaghela, Divyakant Patel, H. Soni, M. Zaveri
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Abstract

Musculoskeletal injuries are most common risk factors for sport persons. Pain and swelling are the most common associated symptoms of such injuries. A use of non-steroidal anti-inflammatory drugs (NSAIDs) has been routine in the management of musculoskeletal inflammation and pain. Although effective at reducing pain and inflammation, NSAIDs may not be appropriate to use frequently or longer time due to their known side effects. Herbal and Ayurveda products are widely perceived as safe due to their natural origin and long historical clinical use. Hence in the present study, different quality control parameters for raw material and finished product (polyherbal pain reliever cream) were evaluated like Acid value, Saponification Value, Free fatty acid determination, Viscosity, Specific gravity, Refractive index, Moisture content, Analysis of heavy metals performed. Finger printing profile for the Oils which includes raw ingredients & finish products both. All data from results suggest that cream and its composition were consistent with various quality and purity parameters such as organoleptic characters, physicochemical parameter, fingerprinting analysis, Quantification of methanol in formulation, Heavy metal analysis and Microbial analysis.
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中药镇痛乳膏的详细质量控制评价
肌肉骨骼损伤是运动员最常见的危险因素。疼痛和肿胀是此类损伤最常见的相关症状。非甾体抗炎药(NSAIDs)的使用已成为治疗肌肉骨骼炎症和疼痛的常规方法。尽管非甾体抗炎药在减轻疼痛和炎症方面有效,但由于其已知的副作用,可能不适合频繁或长时间使用。草药和阿育吠陀产品被广泛认为是安全的,因为它们的天然来源和长期的临床使用历史。因此,本研究对原料和成品(多药镇痛膏)进行了酸值、皂化值、游离脂肪酸测定、粘度、比重、折射率、水分含量、重金属分析等不同质量控制参数的评价。指纹识别油,包括原料和成品。结果表明,乳膏及其成分与感官特性、理化参数、指纹图谱分析、配方中甲醇定量、重金属分析和微生物分析等质量纯度参数一致。
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