FORMULASI DAN UJI AKTIVITAS ANTI BAKTERI SEDIAAN SALEP EKSTRAK ETANOL DAUN SIRIH CINA (peperomia pellucida) TERHADAP BAKTERI Staphylococcus Aureus

Jurnal Penelitian Farmasi & Herbal Pub Date : 2022-04-28 DOI:10.36656/jpfh.v4i2.856

R. Sari

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Abstract

Chinese betel leaf (Peperomiapellucida) is one among the wild herbaceous plants belonging to the Piperaceae family which is employed as a natural medicine. The study's goal was to determine the antibacterial activity of an ethanol extract of Chinese betel leaf ointment against Staphylococcus aureus, as well as the optimal concentration. The test of the study was administered by the diffusion method using disc paper. The results of the characterization examination of Chinese betel leaf simplicia powder obtained water soluble extract content of 64.58%, ethanol soluble extract content of 24.95%, total ash content of three 3.2%, 5.9 % water of content and 0.28% acid insoluble ash content of and Simplisia contains alkaloids, flavonoids, tannins, and saponins. Staphylococcus aureus obtained a degree of 8% with a diameter of 16.81, the diameter of the inhibition zone of the Chinese betel leaf ethanol extract against. The ethanol extract of Chinese betel leaf exhibits antibacterial action against Staphylococcus aureus, according to the findings of the study. Keywords: Antibacterial activity, Chinese betel leaf Staphylococcus aureus

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用于抗菌活性的配方和测试

槟榔叶(Peperomiapellucida)是胡椒科野生草本植物之一，具有天然药用价值。研究槟榔叶软膏乙醇提取物对金黄色葡萄球菌的抑菌活性及最佳浓度。本研究采用纸片扩散法进行试验。表征检验结果表明，菝葜根茎叶粉水溶性提取物含量为64.58%，乙醇可溶性提取物含量为24.95%，总灰分含量为3.2%，水溶灰分含量为5.9%，酸不溶灰分含量为0.28%，菝葜根茎叶中含有生物碱、黄酮类、单宁和皂苷。对金黄色葡萄球菌的抑制度为8%，直径为16.81，槟榔叶乙醇提取物对金黄色葡萄球菌的抑制带直径为16.81。研究发现，槟榔叶乙醇提取物对金黄色葡萄球菌具有抗菌作用。关键词:抗菌活性;槟榔叶;金黄色葡萄球菌

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Jurnal Penelitian Farmasi & Herbal

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