{"title":"COPD: new treatment strategies","authors":"Patrick Mallia MD, PhD, Sebastian L Johnston MBBS, PhD","doi":"10.1002/fps.104","DOIUrl":null,"url":null,"abstract":"<p>Chronic obstructive pulmonary disease (COPD) is a major public health problem that is projected to be the third leading cause of mortality by 2030. The most common aetiological factor related to the development of COPD is tobacco smoking, but exposure to burning biomass and outdoor air pollution are also major risk factors. The prevalence of COPD is projected to increase due to continued exposure to these risk factors and the aging of the world's population. The molecular mechanisms underlying the pathogenesis of COPD are complex and poorly understood and this has hampered the development of new therapies. Copyright © 2013 John Wiley & Sons, Ltd.</p>","PeriodicalId":100566,"journal":{"name":"Future Prescriber","volume":"14 1","pages":"13-16"},"PeriodicalIF":0.0000,"publicationDate":"2013-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/fps.104","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future Prescriber","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/fps.104","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
Chronic obstructive pulmonary disease (COPD) is a major public health problem that is projected to be the third leading cause of mortality by 2030. The most common aetiological factor related to the development of COPD is tobacco smoking, but exposure to burning biomass and outdoor air pollution are also major risk factors. The prevalence of COPD is projected to increase due to continued exposure to these risk factors and the aging of the world's population. The molecular mechanisms underlying the pathogenesis of COPD are complex and poorly understood and this has hampered the development of new therapies. Copyright © 2013 John Wiley & Sons, Ltd.
COPD:新的治疗策略
慢性阻塞性肺疾病是一个重大的公共卫生问题,预计到2030年将成为第三大死亡原因。与慢性阻塞性肺病发展相关的最常见病因因素是吸烟,但暴露于燃烧生物质和室外空气污染也是主要危险因素。由于持续暴露于这些危险因素和世界人口老龄化,预计慢性阻塞性肺病的患病率将增加。慢性阻塞性肺病发病机制的分子机制复杂且知之甚少,这阻碍了新疗法的发展。版权所有©2013 John Wiley &儿子,有限公司
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