Outflow Reconstruction Techniques in Living Donor Liver Transplantation

E. Dulundu
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Abstract

Liver transplantation is a therapeutic option for acute and chronic end stage liver diseases and certain hepatic malignant tumors. The growing disparity between the number of liver transplant candidates and the supply of deceased donor organs has led the increase living donor liver transplantation (LDLT). The provision of an adequate outflow is indispensable for graft function. In order to meet the metabolic demand of the recipient, the majority of the transplant centers switched to a right lobe from the left lobe LDLT which makes hepatic venous reconstruction more complicated. Additionally, the regenerative process of the hepatic allograft may lead dynamic changes in the spatial orientation of reconstructed blood vessels, especially the hepatic venous outflow. Different technical approaches and algorithms have been developed to prevent graft congestion and to perform a sufficient outflow reconstruction. In this review, several considerations of outflow reconstruction techniques are discussed on the basis of our experience and the literature.
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活体供肝移植血流重建技术
肝移植是急性和慢性终末期肝病及某些肝脏恶性肿瘤的治疗选择。肝移植候选者数量与死者供体器官供应之间日益增长的差距导致了活体肝移植(LDLT)的增加。提供足够的流出对移植物功能是必不可少的。为了满足受体的代谢需求,大多数移植中心将左叶LDLT改为右叶LDLT,这使得肝静脉重建更加复杂。此外,同种异体肝移植的再生过程可能导致重建血管的空间取向发生动态变化,尤其是肝静脉流出。不同的技术方法和算法已经开发,以防止移植物堵塞和执行充分的流出重建。在这篇综述中,根据我们的经验和文献讨论了流出口重建技术的几个注意事项。
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来源期刊
Surgery, Gastroenterology and Oncology
Surgery, Gastroenterology and Oncology Medicine-Gastroenterology
CiteScore
0.30
自引率
0.00%
发文量
11
期刊介绍: Starting with this issue "Annals of Fundeni Hospital", founded in 1996 as the scientific journal of the prestigious hospital Fundeni becomes "Journal of Translational Medicine and Research" (JTMR), an Journal of the Academy of Medical Sciences of Romania. Therefore, an 18 years old Journal, attested and indexed in Elsevier Bibliographic Databases, Amsterdam and also indexed in SCOPUS, is continuing a tradition of excellence that lasted almost two decades. The new title of the Journal is inspired first of all from the important developments of translational research In Fundeni Clinical Institute and the "C.C Iliescu Institute for Cardio-Vascular Diseases", in parallel with the national and international trend to promote and develop this important area or medical research. Although devoted mainly to translational research, JTMR will continue to promote both basic and clinical research.
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