The role of PET/CT for detection of distant metastases in malignant epitelial head and neck cancer

T. Yordanova
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Abstract

The aim of our study was to investigate the role of 18F-FDG PET/CT for detection of distant metastases from malignant epitelial head and neck cancer. Methods We analized 205 patients who underwent PET/CT in our clinic for pretreatment staging, restaging between 2015-2017. Patients with positive findings of PET/CT underwent further imaging or biopsy. Results Of the 205 patients and 308 PET/CT exams (166 men and 39 women), 18 had distant metastases. There was 1 false positive result, 186 true negative and no false negative results. PET/CT had a sensitivity of 100%, a specificity of 99.4%, PPV of 94.7%, NPV of 100% and accuracy of 99.5%. Conclusion PET/CT is a useful screening imaging tool for detection of distant metastases in patients with malignant epitelial head and neck cancer.
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PET/CT在恶性上皮性头颈癌远处转移检测中的作用
我们的研究目的是探讨18F-FDG PET/CT在恶性上皮性头颈部癌远处转移检测中的作用。方法对2015-2017年在我院接受PET/CT检查的205例患者进行预处理分期、再分期分析。PET/CT阳性的患者接受进一步的影像学检查或活检。结果205例患者和308例PET/CT检查(男性166例,女性39例)中,18例远处转移。假阳性1例,真阴性186例,无假阴性结果。PET/CT的敏感性为100%,特异性为99.4%,PPV为94.7%,NPV为100%,准确率为99.5%。结论PET/CT是检测恶性上皮性头颈癌远处转移的有效筛查手段。
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