Role of Cinnamon Supplementation on Glycemic Markers, Lipid Profile and Weight Status in Patients with Type II Diabetes

IF 1.2 Q3 MULTIDISCIPLINARY SCIENCES ARO-THE SCIENTIFIC JOURNAL OF KOYA UNIVERSITY Pub Date : 2023-01-15 DOI:10.14500/aro.11041
Sazan M. Talaat
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Abstract

Type II diabetes has been on the rise for the past few decades and the current management plan of diabetes is challenging to individuals in keeping their blood glucose levels within normal limits. There is a constant search of new ways to tackle these challenges. Cinnamon is suggested to have antihyperglycemic and lipid lowering effect and has been proposed to be utilized in type II diabetes. The aim behind this review is to explore the role of cinnamon in improving the glycemic status, lipid profile, and weight status of patients with type II diabetes. PubMed and ScienceDirect databases have been searched for eligible studies conducted until February 2022, the outcomes measured were glycemic markers as primary outcome and lipid profile and weight status as secondary outcomes. A total of ten trials involving 861 patients were included in the study. Five studies have demonstrated reductions in glycemic markers (ranging between −0.56 and −1.9 mmol/L for fasting blood sugar and between −0.21% and −0.93% for glycated hemoglobin) whereas the remaining four did not show any significant reduction. The most improvements in glycemic markers are seen in patients with poorly controlled diabetes and patients with higher body mass index (BMI) values. The majority of the studies did not record improvement in lipid profile. Changes in weight status are only observed in overweight patient category (BMI between 25 and 30). Overall, there is no coherent evidence to decide about antihyperglycemic, lipid lowering, and weight reducing effects of cinnamon in type II diabetes. 
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肉桂补充剂对II型糖尿病患者血糖指标、血脂和体重状况的影响
在过去的几十年里,II型糖尿病的发病率一直呈上升趋势,目前的糖尿病管理计划对保持血糖水平在正常范围内的个体具有挑战性。人们一直在寻找新的方法来应对这些挑战。肉桂被认为具有降糖降脂作用,并被建议用于II型糖尿病。本综述的目的是探讨肉桂在改善II型糖尿病患者的血糖状态、血脂和体重状况方面的作用。PubMed和ScienceDirect数据库检索了截至2022年2月的符合条件的研究,测量的结果是血糖指标作为主要结果,脂质谱和体重状况作为次要结果。该研究共纳入了10项试验,涉及861名患者。五项研究表明血糖指标降低(空腹血糖在- 0.56至- 1.9 mmol/L之间,糖化血红蛋白在- 0.21%至- 0.93%之间),而其余四项研究没有显示任何显著降低。血糖指标改善最明显的是控制不佳的糖尿病患者和体重指数(BMI)较高的患者。大多数研究没有记录到血脂的改善。体重状况的变化仅在超重患者类别(BMI在25至30之间)中观察到。总的来说,没有一致的证据来确定肉桂对II型糖尿病的降糖、降脂和减肥作用。
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来源期刊
ARO-THE SCIENTIFIC JOURNAL OF KOYA UNIVERSITY
ARO-THE SCIENTIFIC JOURNAL OF KOYA UNIVERSITY MULTIDISCIPLINARY SCIENCES-
自引率
33.30%
发文量
33
审稿时长
16 weeks
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