Advanced simulation of an insulin & glucagon pump

Faraz Islam, Abdul Hameed Ahmedulla Khan, Nishita Singh, Alabbas Alhaj Ali
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Abstract

Diabetes is an incurable disease where the body is not able to maintain the blood sugar level as the glucose in the blood is not utilize due to the destruction of the beta pancreatic cell of the liver. Blood sugar level of body is a very important factor for health and it should be maintain within the desired level or else this would result in complications and often serious damage to the body. Therefore treatment must be provided in case of high or low blood sugar level. In case of high blood sugar level, insulin must be injected and in case of low blood sugar level we should inject glucagon into the body. This paper is concerned on advanced method of simulation that can be used to implement a real insulin and glucagon pump that can work in real time to prevent the fatal effects of diabetes on body. This system also covers all the safety critical system aspect required to build a system that has a direct effect on human life. To provide better insulin and glucagon management and to reduce the need for human supervision, we have implement a control algorithm for the insulin and glucagon pump to automate the delivery process. The control algorithm adapts the glucose metabolic rate and determine the appropriate amount of insulin or glucagon to be delivered into the body. Method that is followed is effective and efficient in maintaining the blood sugar level. The Graphical User Interface (GUI) of the system is very easy and user friendly that makes it easier for the patient and doctor to use. Different sets of testing were used to insure the safety and efficiency of the insulin pump simulation.
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胰岛素和胰高血糖素泵的高级模拟
糖尿病是一种无法治愈的疾病,由于肝脏的胰岛细胞被破坏,血液中的葡萄糖不能被利用,身体无法维持血糖水平。身体的血糖水平是健康的一个非常重要的因素,它应该保持在理想的水平,否则会导致并发症,往往对身体造成严重损害。因此,无论血糖水平高或低,都必须进行治疗。如果血糖水平高,必须注射胰岛素,如果血糖水平低,我们应该注射胰高血糖素。本文研究了一种先进的模拟方法,可以用来实现一个真正的胰岛素和胰高血糖素泵,该泵可以实时工作,以防止糖尿病对身体的致命影响。该系统还涵盖了建立一个直接影响人类生活的系统所需的所有安全关键系统方面。为了提供更好的胰岛素和胰高血糖素管理,并减少对人类监督的需要,我们实现了胰岛素和胰高血糖素泵的控制算法,以实现输送过程的自动化。控制算法调整葡萄糖代谢率,并确定适当的胰岛素或胰高血糖素输送到体内。所采用的方法对维持血糖水平是有效的。该系统的图形用户界面(GUI)非常简单,用户友好,使患者和医生更容易使用。为了保证胰岛素泵模拟的安全性和有效性,采用了不同的测试方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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