Clinical presentation of bullous systemic lupus erythematosus in a pediatric patient: a case report

Diana M. Ibarra Tostado, Alejandra Romero Parra, Marisol Padilla Ramirez, Sharira M. Lopez Lopez, Diana L. Macias Cedeño, Cinthya P. Reyes Enriquez, Maria J. Zorrilla Marina, J. M. Zepeda Torres
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Abstract

Bullous systemic lupus erythematosus (BSLE) is a rare blistering eruption that can occur in patients with systemic lupus erythematosus. Although 59 to 85% of patients will have skin manifestations, less than 5% will develop the bullous disease, which is even rarer (1%) in the pediatric population. We present the case of a 16-year-old female patient in whom a diagnosis of BSLE was made through clinical presentation, histological study by biopsy, and direct immunofluorescence. Due to the low incidence of cases reported in pediatric patients, it is possible that the diagnosis may not be made immediately, which is why we emphasize the importance of obtaining an accurate diagnosis and providing timely treatment.
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小儿大疱性系统性红斑狼疮的临床表现:1例报告
大疱性系统性红斑狼疮(BSLE)是一种罕见的水泡疹,可发生在系统性红斑狼疮患者。虽然59 - 85%的患者会有皮肤表现,但只有不到5%的患者会发展成大疱性疾病,这在儿科人群中更为罕见(1%)。我们报告一例16岁的女性患者,她通过临床表现、活检组织学研究和直接免疫荧光诊断为BSLE。由于儿科患者报告的病例发生率较低,因此可能无法立即做出诊断,这就是为什么我们强调获得准确诊断和及时治疗的重要性。
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