Outcomes of hospitalized COVID-19 patients belonging to ethnic/racial minorities in Greece
Michaella Alexandrou, S. Daskalopoulou, Anna-Louiza Haliassou, E. Kranidioti, E. Margellou, A. Panagopoulos, E. Papageorgiou, Artemis Rodopoulou, G. Stavropoulou, Apostolos G. Pappas, I. Kalomenidis
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Abstract
INTRODUCTION Research suggests that racial minorities are overrepresented in the number of COVID-19 related deaths compared to people of White origin. This is the first study to assess racial differences in the clinical characteristics and outcomes of COVID-19 positive patients, hospitalized in Greece. METHODS This retrospective, cross-sectional study included 628 COVID-19 hospitalized patients, from 10 September to 31 December 2020. We compared data concerning gender, age, comorbidities and outcome, between patients of European and non-European origin. Moreover, we applied logistic regression in which the outcome, in our case in-hospital death, was assessed with race, age, sex, and Charlson Comorbidity Index (CCI) score. RESULTS In the first and unadjusted race-only logistic regression model, non-Europeans (OR=0.057;95% CI: 0.008-0.411, p=0.005) were less likely than European patients to die in the hospital. However, controlling for sex, age and CCI score resulted in non-significant differences. CONCLUSIONS There are a lot of statistically significant differences between European and non-European COVID-19 hospitalized patients regarding their clinical characteristics, with the second presenting a lower hospital mortality rate, but after adjusting for age, sex and CCI score, race seems to be not significant. Copyright © 2022 Alexandrou M. et al.
希腊少数民族/种族住院COVID-19患者的结局
研究表明,与白人相比,少数民族在COVID-19相关死亡人数中所占比例过高。这是第一项评估在希腊住院的COVID-19阳性患者临床特征和结果的种族差异的研究。方法本回顾性横断面研究纳入了2020年9月10日至12月31日期间住院的628例COVID-19患者。我们比较了欧洲和非欧洲患者的性别、年龄、合并症和预后数据。此外,我们应用逻辑回归,在我们的病例中,用种族、年龄、性别和Charlson合并症指数(CCI)评分来评估结果。结果在第一个未经调整的纯种族logistic回归模型中,非欧洲患者(OR=0.057;95% CI: 0.008-0.411, p=0.005)在医院死亡的可能性低于欧洲患者。然而,在控制性别、年龄和CCI评分后,差异不显著。结论欧洲与非欧洲住院患者的临床特征有很多统计学意义上的差异,其中欧洲住院患者的医院死亡率较低,但在调整年龄、性别和CCI评分后,种族差异似乎不显著。版权所有©2022 Alexandrou M. et al。
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