A Personalized Diagnostic Tool for Microbiome-Related Morbidities

Olympia Giannou
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Abstract

: A model-driven approach suitable for classifying microbiome-related morbidities such as ulcerative colitis on smart mobile devices is investigated in this manuscript. A novel scheme is proposed, which consists of a pre-trained image classifier on ImageNet and is deployed into the presented Android mobile application for this purpose. Endoscopic images of mouse colitis were used as input datasets for our experiments. The proposed approach offers an efficient classifier, based on the average of all its performance metrics: confusion matrix, accuracy, recall, precision, cross entropy, f1-score. The results are compared with these of the most representative image classifiers for the kind of classification we target, in terms of performance, as well as the size of the retrained frozen graph on our dataset. Such a classification could serve as a valuable tool in clinical medicine offering an automated, diagnostic tool for microbiome-related morbidities, thus allowing accurate early diagnosis and the design of personalized and targeted therapeutic approaches.
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微生物组相关疾病的个性化诊断工具
一种模型驱动的方法适合于分类微生物组相关的发病率,如溃疡性结肠炎在智能移动设备上进行了研究。提出了一种基于ImageNet的预训练图像分类器的新方案,并将其部署到Android移动应用程序中。小鼠结肠炎的内镜图像被用作我们实验的输入数据集。该方法提供了一个高效的分类器,基于其所有性能指标的平均值:混淆矩阵,准确性,召回率,精度,交叉熵,f1-score。将结果与我们目标分类类型的最具代表性的图像分类器进行比较,在性能方面,以及在我们的数据集中重新训练的冻结图的大小。这种分类可以作为临床医学中有价值的工具,为微生物组相关疾病提供自动化诊断工具,从而实现准确的早期诊断和个性化和靶向治疗方法的设计。
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