Screening of children saliva samples for bisphenol A using stochastic, amperometric and multimode microsensors

Abstract

Bisphenol A found in plastic vessels used for children feeding is an endocrine disrupting compound. Therefore it can also induce the obesity at a very early stage in the life of children, and its presence in children saliva should be checked. We proposed eight microsensors: four stochastic microsensors, one amperometric microsensor and three multimode microsensors for the screening of children saliva for bisphenol A in a concentration range from 10⁻¹⁵ to 10⁻⁴ mol/L. Qualitative assessment of bisphenol A in saliva samples was done using stochastic sensing, while its quantitative assessment was done using differential pulse voltammetry and stochastic sensing. The results correlated well, and also compared with those obtained using the standard method, although the standard method did not cover all the time the ranges on which bisphenol A is present in children saliva, and therefore the standard method cannot be reliable used for it analysis in children saliva.