HEPATOPROTECTIVE ACTIVITY OF BAUHINIA RACEMOSA ROOTS EXTRACTS

Abstract

Of all types of plants, we come across everyday every plant is useful some more than other. Our predecessors left an ocean of knowledge regarding the usage of natural sources for medicinal purposes all that we need is, to work on the molecular level to better understand how to avoid negative effects. In the present study Chloroform and Ethanolic extracts of Bauhinia racemosa obtained by soxhlation were used in the determination of Hepatoprotective activity using Paracetamol induced hepatotoxicity method. Oral administration of Bauhinia racemosa Chloroform extract and Bauhinia racemosa Ethanolic Extract showed significant decrease in biochemical parameters such as the ALT, AST, ALP. Animals treated with Ethanolic extract at dose level of 200 mg/kg & 400 mg/kg b.w, p.o in Hepatotoxicity induced rats exhibited a significant reduction of ALP (178.2±1.65 & 169.1±1.88), AST (123.5±1.87 & 115.7±1.25), ALT (115.2±0.94 & 111.4±1.29) respectively. Extensive literature review showed that Bauhinia racemosa is capable of several pharmacological activities and the present study sheds light on the hepatoprotective nature of the selected plant.