R. H. B. Setiarto, Nunuk Widhyastuti, Nandani Dwi Octavia, H. C. Himawan
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引用次数: 3
Abstract
Probiotic beverages can be used as antihipercholesterolemia therapy. One potential ingredient for probiotic drinks is papaya (Carica papaya) which can be fermented using lactic acid bacteria. The aim of this research is to get the right mixture of lactic acid bacteria culture formula to produce probiotic papaya juice which can decrease total cholesterol level in white rats (Rattus norvegicus) of Sprague Dawley strain. The papaya juice is fermented using a mixed culture formulation of different lactic acid bacteria, comprising A (Lactobacillus bulgaricus: Lactobacillus acidophilus: Streptococcus thermophilus); B (Lactobacillus plantarum: Lactobacillus acidophilus: Streptococcus thermophilus); C (Lactobacillus casei: Lactobacillus acidophilus: Streptococcus thermophilus). The results showed that the best formula of probiotic papaya juice mixed using A mixture culture based on pH parameter, total lactic acid and total lactic acid bacteria. After the total cholesterol test, the results obtained that probiotic papaya juice beverage can reduce total cholesterol levels with a decrease percentage of 17.51%. Probiotic papaya juice beverage can be applied to antihipercholesterolemia therapy in humans at doses of 55.56 ml each day. Abstrak Minuman probiotik dapat digunakan sebagai terapi antihiperkolesterolemia. Salah satu bahan potensial untuk minuman probiotik yaitu pepaya ( Carica papaya ) yang dapat difermentasi menggunakan bakteri asam laktat. Tujuan penelitian ini adalah memperoleh formula kultur campuran bakteri asam laktat yang tepat untuk memproduksi minuman sari pepaya probiotik yang mampu menurunkan kadar kolesterol total pada tikus putih ( Rattus norvegicus ) jantan galur Sprague Dawley. Sari pepaya difermentasi menggunakan formulasi kultur campuran bakteri asam laktat yang berbeda, terdiri dari A ( Lactobacillus bulgaricus: Lactobacillus acidophilus: Streptococcus thermophilus ); B ( Lactobacillus plantarum: Lactobacillus acidophilus: Streptococcus thermophilus ); C ( Lactobacillus casei: Lactobacillus acidophilus: Streptococcus thermophilus ). Hasil penelitian menunjukkan bahwa formula terbaik minuman sari pepaya probiotik menggunakan kultur campuran A berdasarkan parameter pH, total asam laktat dan total bakteri asam laktat. Setelah dilakukan uji kolesterol total, maka didapatkan hasil bahwa minuman sari pepaya probiotik dapat menurunkan kadar kolesterol total dengan persentase penurunan sebesar 17,51%. Minuman sari pepaya probiotik dapat diaplikasikan untuk terapi antihiperkolesterolemia pada manusia dengan dosis sebesar 55,56 ml per hari.
益生菌饮料可用于抗高胆固醇血症的治疗。益生菌饮料的一个潜在成分是木瓜(Carica papaya),它可以用乳酸菌发酵。本研究的目的是获得合适的乳酸菌培养配方,以生产能降低褐家鼠(Rattus norvegicus) Sprague Dawley菌株总胆固醇水平的益生菌木瓜汁。所述木瓜汁使用不同乳酸菌的混合培养配方发酵,所述乳酸菌包括a(保加利亚乳杆菌:嗜酸乳杆菌:嗜热链球菌);B(植物乳杆菌、嗜酸乳杆菌、嗜热链球菌);C(干酪乳杆菌、嗜酸乳杆菌、嗜热链球菌)。结果表明,以pH参数、乳酸总量和乳酸菌总量为指标,A型混合培养木瓜益生菌汁的最佳配方。总胆固醇测试结果表明,益生菌木瓜汁饮料可降低总胆固醇水平,降低率为17.51%。益生菌木瓜果汁饮料可用于抗高胆固醇血症的治疗,剂量为每天55.56毫升。【摘要】微益生菌抗高胆固醇血症。Salah satu bahan潜在的人类益生菌yyitu pepaya (Carica papaya) yang dapat的分化与孟古纳肯bakteri asam laktat。褐家鼠(Rattus norvegicus)总褐家鼠(jantan galur Sprague Dawley)配方栽培、campuran bakteri、asam laktat、campuran bakteri、minuman、sari、pepaya、益生菌、yang mampu、menurunkan、kadar、胆固醇。保加利亚乳杆菌:嗜酸乳杆菌;嗜热链球菌;保加利亚乳杆菌;B(植物乳杆菌、嗜酸乳杆菌、嗜热链球菌);C(干酪乳杆菌、嗜酸乳杆菌、嗜热链球菌)。Hasil penelitian menunjukkan bahwa配方terbaik minuman sari pepaya mongunakan培养菌campuran berdasarkan参数pH、总阿萨姆拉达克和总阿萨姆拉达克。Setelah dilakukan uji胆固醇总量,maka didapatkan hasil bahwa minuman sari pepaya probiotik dapat menurunkan kadar胆固醇总量和代表酶penurunan sebesar 17.51%。米诺米沙利菌制剂,抗高胆固醇血症,糖尿病邓根剂量为55,56 ml / hari。