The Gestational Diabetes Mellitus Approach in Clinical Practice – A Narrative Review

Q4 Pharmacology, Toxicology and Pharmaceutics Acta Marisiensis - Seria Medica Pub Date : 2021-12-01 DOI:10.2478/amma-2021-0037
Oana Deteșan, Lucia Mihaela Custură, Reka Annamaria Schmiedt, Brigitta Irén Bacso, A. C. Bell, Maria Alexandra Streza, M. Tilinca
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Abstract

Abstract Gestational diabetes mellitus (GDM) is an increasingly condition in medical practice. In the absence of an effective therapeutic management, it can lead to significant maternal and neonatal complications with adverse health effects. Reducing the risk of morbidity is the goal achived by screening of all pregnant women and active involvement of health care staff and early medical intervention in case of detection of GDM. The aim of this review is to present the nowadays strategy of GDM approach. The management challenge is to maintain blood glucose levels within the targets recommended by current guidelines, which are in relatively narrow ranges. Nutritional intervention and lifestyle changes are of primary importance. If necessary insulin therapy is initiated, insulin analogues are preferable due to lower risk of hypoglycemia. Oral antidiabetics are not recommended in pregnancy, even if they are used in certain circumstances.
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妊娠期糖尿病治疗方法的临床应用综述
妊娠期糖尿病(GDM)在医学实践中日益受到重视。在缺乏有效治疗管理的情况下,它可能导致严重的孕产妇和新生儿并发症,对健康产生不利影响。通过对所有孕妇进行筛查、保健工作人员的积极参与以及在发现妊娠糖尿病时进行早期医疗干预,可以实现降低发病率风险的目标。这篇综述的目的是介绍当前GDM方法的策略。管理上的挑战是维持血糖水平在当前指南推荐的目标范围内,这是一个相对狭窄的范围。营养干预和生活方式的改变至关重要。如果开始必要的胰岛素治疗,胰岛素类似物是可取的,因为低血糖的风险较低。妊娠期不建议服用口服抗糖尿病药,即使在某些情况下也不建议服用。
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来源期刊
Acta Marisiensis - Seria Medica
Acta Marisiensis - Seria Medica Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
0.40
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审稿时长
24 weeks
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