A sensitivity analysis of a gonorrhoea dynamics and control model

L. Omenyi, Aloysius Ezaka, Henry O. Adagba, G. Ozoigbo, Kafayat Elebute
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Abstract

We formulate and analyse a robust mathematical model of the dynamics of gonorrhoea incorporating passive immunity and control. Our results show that the disease-free and endemic equilibria of the model are both locally and globally asymptotically stable. A sensitivity analysis of the model shows that the dynamics of the model is variable and dependent on waning rate, control parameters and interaction of the latent and infected classes. In particular, the lower the waning rate, the more the exponential decrease in the passive immunity but the susceptible population increases to the equilibrium and wanes asymptotically due to the presence of the control parameters and restricted interaction of the latent and infected classes.
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淋病动力学和控制模型的敏感性分析
我们制定和分析淋病纳入被动免疫和控制动力学的一个强大的数学模型。结果表明,该模型的无病平衡点和地方性平衡点是局部和全局渐近稳定的。模型的敏感性分析表明,模型的动力学是可变的,并取决于衰减率、控制参数以及潜伏类和感染类的相互作用。特别是,衰减率越低,被动免疫指数下降越大,但由于控制参数的存在和潜伏类与感染类之间有限的相互作用,易感群体逐渐增加到平衡状态并逐渐减弱。
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