Methadone-Induced QT Interval Prolongation and Torsades de Pointes

S. Tabaghi, M. Akbarzadeh
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引用次数: 0

Abstract

: The most common cause of acquired long QT syndrome in patients without physiological and structural cardiovascular disease is the use of medications. Chronic high-dose methadone usage can cause prolongation of QT interval that may provoke the life-threatening arrhythmia Torsades de Pointes. In this study, we present a 41-year-old man with chronic high-dose methadone usage who developed Torsades de Pointes triggered by short-coupled premature ventricular contraction.
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美沙酮诱导的QT间期延长和点扭转
在没有生理性和结构性心血管疾病的患者中,获得性长QT综合征最常见的原因是药物的使用。长期大剂量使用美沙酮可引起QT间期延长,可引起危及生命的心律失常。在这项研究中,我们报告了一名41岁的长期高剂量美沙酮患者,他因短偶联室性早衰而发展为角性扭转。
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