Inflammation in diabetes and cardiovascular disease: a new perspective on vitamin D

Lei Su, Haipeng Xiao
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引用次数: 3

Abstract

Epidemiological studies indicate an inverse association between vitamin D level and chronic, low-grade systemic inflammatory diseases, such as type 2 diabetes mellitus and cardiovascular disease. Vitamin D signaling may interfere with transcription factors, such as nuclear factor-kappa B, which regulate the expression of inflammatory markers at several levels. In this review, the latest advances in the anti-inflammatory effects of vitamin D from experimental, observational, and small interventional studies will be discussed.
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糖尿病和心血管疾病中的炎症:维生素D的新视角
流行病学研究表明,维生素D水平与慢性、低级别全身性炎症疾病(如2型糖尿病和心血管疾病)呈负相关。维生素D信号可能会干扰转录因子,如核因子κ B,其在多个水平上调节炎症标志物的表达。本文将从实验、观察和小型介入性研究等方面对维生素D抗炎作用的最新进展进行综述。
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Prevalence of cardiovascular disease and evaluation of standard of care in type 2 diabetes: a nationwide study in primary care. Oxford Diabetes Symposium 2017. Androgenic alopecia, premature graying, and hair thinning as independent predictors of coronary artery disease in young Asian males The association of vitamin D status and dietary calcium intake with individual components of the metabolic syndrome: a population-based study in Victoria, Australia Chronic kidney disease-associated cardiovascular disease: scope and limitations of animal models
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