Insecticidal thioureas: Preparation and biochemical impacts of some novel thiobenzamide derivatives as potential eco-friendly insecticidal against the cotton leafworm, Spodoptera littoralis (Boisd.)
Mohamed A Gad, M. Bakry, Eman A Shehata, Noha A. Dabour
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引用次数: 2
Abstract
The following work could bring new insights into the application of heterocyclic N, N′-substituted thiobenzamide derivatives as novel pesticides. Insect growth regulators such as chitin synthesis inhibitors seem promising because of their specific mode of action on insects and their lower toxicity against vertebrates than conventional insecticides. Thus, a novel series of thiobenzamide derivatives have been prepared in a pure state. The structure of these synthesized compounds which related to the most famous insect growth regulator insecticides, were confirmed by elemental and modern spectroscopic analyses (IR, UV, 1HNMR and 13CNMR). Toxicological and biochemical parameters of the synthesized compounds against the cotton leafworm, Spodoptera littoralis under laboratory conditions were also investigated. Regarding the determined LC50 value for compound 2,4-Dichloro-N-[(2-methoxyphenyl)carbamothioyl]- benzamide 14 showed the most potent toxic effects than the other synthetic target compounds, with LC50 46.84 ppm of 2nd instar larvae and LC50 148.05of the 4th instar larvae.
期刊介绍：
The "Current Chemistry Letters" is a peer-reviewed international journal which aims to publish all the current and outstanding research articles, reviews and letters in chemistry including analytical chemistry, green chemistry, inorganic chemistry, organic chemistry, physical chemistry, etc. This journal is dedicated to serve all academic and industrial researchers and scientists who are expert in all major advances in chemistry research. The journal aims to provide the most complete and reliable source of information on current developments in these fields. The emphasis will be on publishing quality articles rapidly and openly available to researchers worldwide. Please note readers are free to read, download, copy, distribute, print, search, or link to the full texts of articles published on this journal. Current Chemistry Letters is an open access journal, which provides instant access to the full text of research papers without any need for a subscription to the journal where the papers are published. Therefore, anyone has the opportunity to copy, use, redistribute, transmit/display the work publicly and to distribute derivative works, in any sort of digital form for any responsible purpose, subject to appropriate attribution of authorship. Authors who publish their articles may also maintain the copyright of their articles.
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