Highly porous composite hydrogel materials β-Ca3(PO4)2/polyethylene glycol diacrylate

P. Evdokimov, A. Kiseleva, A. Shibaev, O. Filippova, E. Novoseletskaya, A. Efimenko, I. M. Scherbakov, G. A. Shipunov, V. Dubrov, V. Putlayev
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Abstract

The possibility of obtaining highly porous composite hydrogel materials for biomedical applications based on tricalcium phosphate in a polyethylene glycol diacrylate matrix, aimed to repair bone defects, was studied. The influence of different contents of inorganic filler particles on the mechanical characteristics of highly porous hydrogel composites β-Ca3(PO4)2/polyethylene glycol diacrylate was studied. The possibility of creating highly porous composite materials with specified elastic properties is demonstrated. The dependence of the viscoelastic properties of the obtained materials on the size of the given porosity is shown. Varying the proportion of tricalcium phosphate in the highly porous hydrogel material makes it possible to control the relative stiffness of the composite.
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高孔复合水凝胶材料β-Ca3(PO4)2/聚乙二醇二丙烯酸酯
研究了以聚乙二醇二丙烯酸酯为基质的磷酸三钙为基础,制备用于骨缺损修复的高孔复合水凝胶材料的可能性。研究了不同无机填充颗粒含量对高孔水凝胶复合材料β-Ca3(PO4)2/聚乙二醇二丙烯酸酯力学性能的影响。证明了制造具有特定弹性性能的高多孔复合材料的可能性。得到的材料的粘弹性特性与给定孔隙率的大小有关。改变磷酸三钙在高多孔水凝胶材料中的比例,可以控制复合材料的相对刚度。
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