Neurological manifestations of cerebral venous thrombosis: experience from a tertiary care center

Anum Irfan, Soban Khan, Zaid Waqar, S. Nabi, Bushra Khalid, Muhammad Tariq
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Abstract

Background and Objective: Cerebral venous thrombosis (CVT) is a common cause of cerebrovascular accident (stroke). CVT is caused due to blockage in blood flow either in cerebral veins or in dural sinuses. The objective of this study was to determine prevalence of various clinical and imaging characteristics in patients with cerebral venous thrombosis. Methods:  A descriptive retrospective cross-sectional patient data was collected from November 2019 to February 2021. This study was conducted in Neurology Department in Pakistan Institute of Medical Sciences (PIMS), Islamabad, Pakistan. This study contains patient medical histories of 60 patients who were admitted in two and a half year time. Monitoring for any seizure occurrence was carried out for all the patients included in this study. Patient medical histories were examined and CT, MRI and MRV Brain were performed. Results:  Superior sagittal sinus was spotted as a hot spot location for CVT. Mean age calculated was 30 while more frequency was recorded in female patients. Conclusion:  CVT is a condition with more prevalence in younger population with more affected females than males. Most common presentation of CVT is headache. Superior sagittal sinuses involved in majority of cases reported. Specificity of modalities used and neurological manifestations needs a validation through a larger cohort study.
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脑静脉血栓的神经学表现:来自三级保健中心的经验
背景与目的:脑静脉血栓形成(CVT)是脑血管意外(脑卒中)的常见原因。CVT是由于脑静脉或硬脑膜窦血流阻塞而引起的。本研究的目的是确定脑静脉血栓形成患者的各种临床和影像学特征的患病率。方法:从2019年11月至2021年2月收集描述性回顾性横断面患者数据。本研究在巴基斯坦伊斯兰堡巴基斯坦医学科学研究所(PIMS)神经内科进行。本研究包含60例在两年半时间内入院的患者的病史。本研究纳入的所有患者均进行癫痫发作监测。检查患者的病史,并进行CT、MRI和MRV脑扫描。结果:发现上矢状窦为CVT的热点部位。计算的平均年龄为30岁,而女性患者记录的频率更高。结论:CVT多发于年轻人群,女性多于男性。CVT最常见的表现是头痛。上矢状窦在大多数病例中被累及。所使用的治疗方法和神经学表现的特异性需要通过更大的队列研究来验证。
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