{"title":"Crystal Structure of 1,3-Bis(p-methylphenyl)-2-flouro-1,3,2-diazaphospholidine-2-oxide","authors":"K. Gholivand, F. Mojahed","doi":"10.2116/ANALSCIX.24.X17","DOIUrl":null,"url":null,"abstract":"Diazaphospholidines have the ability to bind with metals and to inhibit cholinesterase (ChE), an enzyme that has a vital role in nerve impulse transition. The crystal structure of 1,3-bis(p-methylphenyl)-2-flouro-1,3,2-diazaphospholidine-2-oxide (1) was determind using single-crystal X-ray diffraction. The five-membered ring containing phosphorus, nitrogen and carbon atoms is slightly puckered. The coordination environment around the phosphorus atom in this compound is approximately tetrahedral.","PeriodicalId":7796,"journal":{"name":"Analytical Sciences: X-ray Structure Analysis Online","volume":"8 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytical Sciences: X-ray Structure Analysis Online","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2116/ANALSCIX.24.X17","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Diazaphospholidines have the ability to bind with metals and to inhibit cholinesterase (ChE), an enzyme that has a vital role in nerve impulse transition. The crystal structure of 1,3-bis(p-methylphenyl)-2-flouro-1,3,2-diazaphospholidine-2-oxide (1) was determind using single-crystal X-ray diffraction. The five-membered ring containing phosphorus, nitrogen and carbon atoms is slightly puckered. The coordination environment around the phosphorus atom in this compound is approximately tetrahedral.