気管支喘息による入院患者への定量噴霧式吸入剤 (MDI) の吸入指導効果の臨床評価

文良 小嶋, 秀範 中村, 徹 東海林, 仁暢 友池, 義人 仲川
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Abstract

In order to investigate the efficacy of pharmaceutical instruction including the instructions for use of a metered dose inhaler by inpatients with chronic bronchial asthma, intervals of hospital visits, therapeutic scores in the prescription and in the consulting room were assessed in twelve patients who were treated at Yamagata University Hospital. No patients who re-entered the hospital were recognized after their discharge from the hospital (12.8-30.4 months). The mean times of exacerbation needed for the intra-venous injection of steroids and/or aminophylline during the one year period before and after the last hospitalization in which pharmaceutical instructions were given, were 2.8 and 1.6, respectively. One of the 12 patients received the injections for treatment of asthma only one time during the one year period. In seven patients who received oral corticosteroids at discharge, three patients were able to discontinue and two patients were able to decrease their dosage. Although it was difficult to obtain any specific contribution ratio on their clinical efficacy, the pharmaceutical service including usage instruction of the metered dose inhaler by pharmacists to the patients with bronchial asthma was found to be useful especially for patients who had been repeatedly hospitalized.
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支气管哮喘住院患者的定量喷雾式吸入剂(MDI)吸入指导效果的临床评估
为了探讨慢性支气管哮喘住院患者的药物指导(包括计量吸入器的使用指导)的效果,对在山形大学医院接受治疗的12例患者的就诊间隔、处方和咨询室的治疗评分进行了评估。出院后(12.8 ~ 30.4个月)未发现再入院患者。在给予药物指导的最后一次住院前后的一年中,静脉注射类固醇和/或氨茶碱所需的平均加重时间分别为2.8和1.6。12例患者中有1例在一年的时间里只接受了一次治疗哮喘的注射。在出院时接受口服皮质类固醇治疗的7名患者中,3名患者能够停药,2名患者能够减少剂量。虽然难以获得其临床疗效的具体贡献率,但发现药师对支气管哮喘患者的药学服务,包括计量吸入器的使用指导,对反复住院的患者尤其有用。
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