{"title":"Diabetic Foot Ulcer Among Adults Attending Follow-Up Diabetes Clinics in Wolaita Zone, Southern Ethiopia: An Unmatched, Case-Control Study","authors":"Lielt Gebreselassie Gebrekirstos MSc , Mulugeta Tsegay Abadi MSc , Meron Hadis Gebremedhin MSc , Eyasu Alem Lake MSc , Tsiyon Birhanu Wube MSc","doi":"10.1016/j.curtheres.2022.100673","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Diabetic foot ulcer is a major public health problem, and among the leading causes of this complication in Ethiopian patients with diabetes. Despite the magnitude of this problem, data regarding the determinants of diabetic foot ulcers are limited.</p></div><div><h3>Objective</h3><p>This study aimed to assess the determinants of diabetic foot ulcers among adults attending follow-up visits in diabetes clinics in the Wolaita Zone, southern Ethiopia.</p></div><div><h3>Methods</h3><p>An institution-based case-control study was done from September 10 to December 28, 2020, in southern Ethiopia. We recruited 137 patients with diabetic foot ulcers and 408 patients without any diabetic foot ulcers using a consecutive sampling method. EpiData version 3.1.1 (EpiData Association, Odense, Denmark) and SPSS version 25 (IBM-SPSS Inc, Armonk, New York) were used for data entry and analysis. Descriptive statistics were calculated followed by a multivariate logistic regression analysis.</p></div><div><h3>Results</h3><p>Having a low wealth index (adjusted odds ratio [AOR] = 2.6; 95% CI, 1.177–5.662); being obese (AOR = 3.6; 95% CI, 1.380–9.547; <em>P =</em> 0.003), being overweight (AOR = 3.1; 95% CI, 1.480–6.436; <em>P =</em> 0.009), having peripheral neuropathy (AOR = 3.9; 95% CI, 1.641–9.430; <em>P =</em> 0.002), living with diabetes for >10 years (AOR = 2.3; 95% CI, 1.191–4.475; <em>P =</em> 0.013), and practicing poor diabetic foot self-care (AOR = 6.0; 95% CI, 3.156–11.312<em>; P =</em> 0.000) were significantly associated with having a diabetic foot ulcer.</p></div><div><h3>Conclusions</h3><p>This study suggests there is a need for education and counseling of patients on decreasing weight and improving foot-care practice, especially in those who are economically disadvantaged, have peripheral neuropathy, and have lived with diabetes for more than 10 years. (<em>Curr Ther Res Clin Exp</em>. 2022; 83:XXX–XXX)</p></div>","PeriodicalId":10920,"journal":{"name":"Current Therapeutic Research-clinical and Experimental","volume":"96 ","pages":"Article 100673"},"PeriodicalIF":1.6000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0011393X22000121/pdfft?md5=798903aaa4fbd1b5025a9d8556951816&pid=1-s2.0-S0011393X22000121-main.pdf","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Therapeutic Research-clinical and Experimental","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0011393X22000121","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 1
Abstract
Background
Diabetic foot ulcer is a major public health problem, and among the leading causes of this complication in Ethiopian patients with diabetes. Despite the magnitude of this problem, data regarding the determinants of diabetic foot ulcers are limited.
Objective
This study aimed to assess the determinants of diabetic foot ulcers among adults attending follow-up visits in diabetes clinics in the Wolaita Zone, southern Ethiopia.
Methods
An institution-based case-control study was done from September 10 to December 28, 2020, in southern Ethiopia. We recruited 137 patients with diabetic foot ulcers and 408 patients without any diabetic foot ulcers using a consecutive sampling method. EpiData version 3.1.1 (EpiData Association, Odense, Denmark) and SPSS version 25 (IBM-SPSS Inc, Armonk, New York) were used for data entry and analysis. Descriptive statistics were calculated followed by a multivariate logistic regression analysis.
Results
Having a low wealth index (adjusted odds ratio [AOR] = 2.6; 95% CI, 1.177–5.662); being obese (AOR = 3.6; 95% CI, 1.380–9.547; P = 0.003), being overweight (AOR = 3.1; 95% CI, 1.480–6.436; P = 0.009), having peripheral neuropathy (AOR = 3.9; 95% CI, 1.641–9.430; P = 0.002), living with diabetes for >10 years (AOR = 2.3; 95% CI, 1.191–4.475; P = 0.013), and practicing poor diabetic foot self-care (AOR = 6.0; 95% CI, 3.156–11.312; P = 0.000) were significantly associated with having a diabetic foot ulcer.
Conclusions
This study suggests there is a need for education and counseling of patients on decreasing weight and improving foot-care practice, especially in those who are economically disadvantaged, have peripheral neuropathy, and have lived with diabetes for more than 10 years. (Curr Ther Res Clin Exp. 2022; 83:XXX–XXX)
期刊介绍:
We also encourage the submission of manuscripts presenting preclinical and very preliminary research that may stimulate further investigation of potentially relevant findings, as well as in-depth review articles on specific therapies or disease states, and applied health delivery or pharmacoeconomics.
CTR encourages and supports the submission of manuscripts describing:
• Interventions designed to understand or improve human health, disease treatment or disease prevention;
• Studies that focus on problems that are uncommon in resource-rich countries;
• Research that is "under-published" because of limited access to monetary resources such as English language support and Open Access fees (CTR offers deeply discounted English language editing);
• Republication of articles previously published in non-English journals (eg, evidence-based guidelines) which could be useful if translated into English;
• Preclinical and clinical product development studies that are not pursued for further investigation based upon early phase results.