Diabetic Foot Ulcer Among Adults Attending Follow-Up Diabetes Clinics in Wolaita Zone, Southern Ethiopia: An Unmatched, Case-Control Study

IF 1.6 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Current Therapeutic Research-clinical and Experimental Pub Date : 2022-01-01 DOI:10.1016/j.curtheres.2022.100673
Lielt Gebreselassie Gebrekirstos MSc , Mulugeta Tsegay Abadi MSc , Meron Hadis Gebremedhin MSc , Eyasu Alem Lake MSc , Tsiyon Birhanu Wube MSc
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引用次数: 1

Abstract

Background

Diabetic foot ulcer is a major public health problem, and among the leading causes of this complication in Ethiopian patients with diabetes. Despite the magnitude of this problem, data regarding the determinants of diabetic foot ulcers are limited.

Objective

This study aimed to assess the determinants of diabetic foot ulcers among adults attending follow-up visits in diabetes clinics in the Wolaita Zone, southern Ethiopia.

Methods

An institution-based case-control study was done from September 10 to December 28, 2020, in southern Ethiopia. We recruited 137 patients with diabetic foot ulcers and 408 patients without any diabetic foot ulcers using a consecutive sampling method. EpiData version 3.1.1 (EpiData Association, Odense, Denmark) and SPSS version 25 (IBM-SPSS Inc, Armonk, New York) were used for data entry and analysis. Descriptive statistics were calculated followed by a multivariate logistic regression analysis.

Results

Having a low wealth index (adjusted odds ratio [AOR] = 2.6; 95% CI, 1.177–5.662); being obese (AOR = 3.6; 95% CI, 1.380–9.547; P = 0.003), being overweight (AOR = 3.1; 95% CI, 1.480–6.436; P = 0.009), having peripheral neuropathy (AOR = 3.9; 95% CI, 1.641–9.430; P = 0.002), living with diabetes for >10 years (AOR = 2.3; 95% CI, 1.191–4.475; P = 0.013), and practicing poor diabetic foot self-care (AOR = 6.0; 95% CI, 3.156–11.312; P = 0.000) were significantly associated with having a diabetic foot ulcer.

Conclusions

This study suggests there is a need for education and counseling of patients on decreasing weight and improving foot-care practice, especially in those who are economically disadvantaged, have peripheral neuropathy, and have lived with diabetes for more than 10 years. (Curr Ther Res Clin Exp. 2022; 83:XXX–XXX)

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在埃塞俄比亚南部Wolaita地区参加糖尿病门诊随访的成人糖尿病足溃疡:一项无与伦比的病例对照研究
背景:糖尿病足溃疡是一个主要的公共卫生问题,也是埃塞俄比亚糖尿病患者并发症的主要原因之一。尽管这个问题的严重性,关于糖尿病足溃疡的决定因素的数据是有限的。目的:本研究旨在评估埃塞俄比亚南部Wolaita地区糖尿病门诊随访的成年人糖尿病足溃疡的决定因素。方法于2020年9月10日至12月28日在埃塞俄比亚南部开展了一项基于机构的病例对照研究。采用连续抽样的方法,我们招募了137例糖尿病足溃疡患者和408例无糖尿病足溃疡的患者。使用EpiData 3.1.1版(EpiData Association,欧登塞,丹麦)和SPSS 25版(IBM-SPSS Inc, Armonk,纽约)进行数据录入和分析。进行描述性统计,然后进行多元逻辑回归分析。结果低财富指数(调整优势比[AOR] = 2.6;95% ci, 1.177-5.662);肥胖(AOR = 3.6;95% ci, 1.380-9.547;P = 0.003),超重(AOR = 3.1;95% ci, 1.480-6.436;P = 0.009),周围神经病变(AOR = 3.9;95% ci, 1.641-9.430;P = 0.002),糖尿病患者≥10年(AOR = 2.3;95% ci, 1.191-4.475;P = 0.013),糖尿病足自我护理不良(AOR = 6.0;95% ci, 3.156-11.312;P = 0.000)与糖尿病足溃疡显著相关。结论有必要对糖尿病患者进行减肥教育和咨询,改善足部护理实践,特别是对经济条件差、周围神经病变和糖尿病患者超过10年的患者。(中国临床医学杂志,2022;83: XXX-XXX)
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来源期刊
CiteScore
3.50
自引率
0.00%
发文量
31
审稿时长
3 months
期刊介绍: We also encourage the submission of manuscripts presenting preclinical and very preliminary research that may stimulate further investigation of potentially relevant findings, as well as in-depth review articles on specific therapies or disease states, and applied health delivery or pharmacoeconomics. CTR encourages and supports the submission of manuscripts describing: • Interventions designed to understand or improve human health, disease treatment or disease prevention; • Studies that focus on problems that are uncommon in resource-rich countries; • Research that is "under-published" because of limited access to monetary resources such as English language support and Open Access fees (CTR offers deeply discounted English language editing); • Republication of articles previously published in non-English journals (eg, evidence-based guidelines) which could be useful if translated into English; • Preclinical and clinical product development studies that are not pursued for further investigation based upon early phase results.
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