Review on chemical composition of gluten-free food for celiac people

A. Maggio, S. Orecchio, S. Barreca
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引用次数: 2

Abstract

Celiac disease (CD) is a common chronic enteropathy disease which affects approximately 1-2% of the word population [1]. CD is intolerance for gluten in genetically predisposed individuals and is characterized by an inappropriate immune response of the T-lymphocytes of the small intestines to gluten peptides [2]. In celiac people, ingestion of gluten leads to inflammation and mucosal damage of the small intestine [3]. The typical lesion in the small intestinal epithelium is villous atrophy with crypt hyperplasia, leading to malabsorption of most nutrients such as minerals (Fe, Ca, Zn, etc.) and others essential components (folic acid, fat-soluble and vitamins) [4]. Today, the only available treatment is a lifelong strict gluten-free diet, which leads to restoration of the atrophied intestinal villi. By removing gluten food from the diet of celiac patients will result, in the majority of cases, a normalization of symptoms and cytological and histological parameters [5]. Generally, coeliac people need assistance from a dietician that has no knowledge on mineral contents or fatty acids, proteins, sugars compositions of available gluten-free products, and, for this reason, it is necessary to know the composition of gluten free foods commonly consumed by individuals with celiac disease.
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乳糜泻患者无麸质食品化学成分研究进展
乳糜泻(乳糜泻)是一种常见的慢性肠病,约占世界人口的1-2%[1]。乳糜泻是遗传易感个体对麸质不耐受,其特征是小肠t淋巴细胞对麸质肽的不适当免疫反应[2]。在乳糜泻患者中,摄入麸质会导致小肠炎症和粘膜损伤[3]。小肠上皮典型病变为绒毛萎缩伴隐窝增生,导致大多数营养物质如矿物质(Fe、Ca、Zn等)和其他必需成分(叶酸、脂溶性和维生素)吸收不良[4]。今天,唯一可用的治疗方法是终生严格的无麸质饮食,这会导致萎缩的肠绒毛的恢复。在大多数情况下,将麸质食物从乳糜泻患者的饮食中去除将导致症状和细胞学和组织学参数的正常化[5]。一般来说,乳糜泻患者需要营养师的帮助他们不了解无谷蛋白产品的矿物质含量,脂肪酸,蛋白质,糖的组成,因此,有必要了解乳糜泻患者通常食用的无谷蛋白食物的组成。
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