Physicochemical characterisation of biosynthetic bacterial cellulose as a potential wound dressing material

Abhishek Gupta, W. Low, S. Britland, I. Radecka, Claire Martin
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引用次数: 8

Abstract

The aim of this study was to characterise the physicochemical and biocompatibility properties of biosynthetic bacterial cellulose (BC) as a potential wound dressing material. The moisture content, water vapour transmission rate (WVTR), thermal stability, cyto- and haemo-compatibility of BC were investigated. Results indicated that the physicochemical properties of biosynthetic BC allow an optimum WVTR to be maintained for improved localised wound moisture levels, good thermal stability and excellent water imbibing capabilities. In vitro cytotoxicity and haemocompatibility confirmed the biocompatibility of BC and hence suitability of this material for further exploration into its’ application as a wound dressing material.
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生物合成细菌纤维素作为潜在创面敷料的理化特性研究
本研究的目的是表征生物合成细菌纤维素(BC)作为潜在伤口敷料的物理化学和生物相容性。研究了BC的含水量、水蒸气透过率(WVTR)、热稳定性、细胞和血液相容性。结果表明,生物合成BC的物理化学性质允许维持最佳的WVTR,以改善局部伤口水分水平,良好的热稳定性和优异的吸水能力。体外细胞毒性和血液相容性证实了BC的生物相容性,因此该材料适合进一步探索其作为伤口敷料的应用。
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