{"title":"A feline case with multiple fibrosarcoma and systemic fibromatosis associated with feline leukemia virus/feline sarcoma virus","authors":"K. Hase, I. Hase, Y. Shimoyama, K. Nishifuji","doi":"10.2736/jjvd.26.75","DOIUrl":null,"url":null,"abstract":"A 3 years and 3 months old, intact male domestic cat was presented with multiple papules and nodules as well as generalized sclerema. Histopathological analysis of the tissue samples obtained by skin biopsy and necropsy revealed an extensive and aggressive proliferation of spindle cells not only in sclerematous skin and the cutaneous nodules, but in skeletal muscle membranes and serosa. The findings in some cutaneous nodules were consistent with those of fibrosarcoma. Immunohistochemical analysis with antifeline leukemia virus revealed cytoplasmic staining of those proliferating spindle cells, suggesting that the histopathological changes were associated with feline leukemia virus or feline sarcoma virus.","PeriodicalId":22603,"journal":{"name":"The Japanese Journal of Veterinary Dermatology","volume":"23 1","pages":"75-78"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Japanese Journal of Veterinary Dermatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2736/jjvd.26.75","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
A 3 years and 3 months old, intact male domestic cat was presented with multiple papules and nodules as well as generalized sclerema. Histopathological analysis of the tissue samples obtained by skin biopsy and necropsy revealed an extensive and aggressive proliferation of spindle cells not only in sclerematous skin and the cutaneous nodules, but in skeletal muscle membranes and serosa. The findings in some cutaneous nodules were consistent with those of fibrosarcoma. Immunohistochemical analysis with antifeline leukemia virus revealed cytoplasmic staining of those proliferating spindle cells, suggesting that the histopathological changes were associated with feline leukemia virus or feline sarcoma virus.
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