EVALUATION OF PLANT-BASED UV FILTERS POTENTIAL IN MODERN CONCEPT VIEW OF SKIN PHOTOPROTECTION

O. D. Nemyatykh, I. I. Terninko, A. Sabitov, A. I. Lyashko, Z. Sakipova
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Abstract

A therapeutic plants potential is based on the pharmacological effects due to their phytochemical profile. Today, scientific interest in botanicals is increasing as a result of recent research that looks at the prospect of using these raw materials for the cosmetic industry as a means to protect the skin from the harmful effects of UV rays.The aim of the study was to evaluate a potential of plant-based UV-filters in modern concept view of skin photoprotection.Materials and methods. A systematic literature search was carried out using the electronic information arrays PubMed, Scopus, Google Scholar, eLibrary. The search depth was 10 years (the period from 2010 to 2021). The search was carried out by the following keywords: antioxidants, cosmetics, photoprotection, chemical composition, pharmacological action.Results. In the paper, modern principles of skin photoprotection based on the use of chemical or physical UV-filters are considered and scientifically substantiated A trend for the use of plant-based materials and their components in the formulation of photoprotectors was notified. That is associated with a wide activity spectrum, the absence of a xenobiotic effect, and a high bioavailability of organic plant compounds.Conclusion. The data analysis from scientific publications demonstrated a potential photoprotective activity of plant-based biologically active substances due to antioxidant, anti-inflammatory and anti-radical effects. The results of the study are a theoretical basis for a further comprehensive experimental study of plant objects in order to obtain a pool of evidence in the field of photoprotection in in vivo experiments.
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从现代皮肤光防护的角度评价植物基紫外线过滤器的潜力
治疗植物的潜力是基于其药理作用,由于它们的植物化学特征。今天,由于最近的研究,科学家对植物药的兴趣正在增加,这些研究着眼于将这些原料用于化妆品工业的前景,作为保护皮肤免受紫外线有害影响的一种手段。该研究的目的是评估植物基紫外线过滤器在现代皮肤光防护概念中的潜力。材料和方法。采用PubMed、Scopus、Google Scholar、library等电子信息阵列进行系统文献检索。搜索深度为10年(2010年至2021年)。以抗氧化剂、化妆品、光防护、化学成分、药理作用等关键词进行检索。摘要现代皮肤光原理的基础上,利用化学或物理紫外线过滤被认为是和科学证实这一趋势使用植物性材料的配方及其组件photoprotectors通知。这与有机植物化合物的广谱活性、无异种效应和高生物利用度有关。来自科学出版物的数据分析表明,由于抗氧化、抗炎和抗自由基作用,植物性生物活性物质具有潜在的光保护活性。本研究结果为进一步对植物对象进行全面的实验研究提供了理论基础,以期在体内实验中获得光保护领域的证据库。
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