Effect of alkaline treatment with sodium hydroxide on wettability and bioactivity of some commercial dental implants: An in-vitro study

M. Morad, S. El-Safty, Eman M. S. Elbahrawy
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Abstract

Aim/Objectives The aim of this study was conducted to evaluate the effect of NaOH alkaline treatment on wettability and bioactivity of some commercial dental implants. Background The surface of titanium dental implants plays an important role in their success. Wettability is one of the crucial surface characteristics for osseointegration. Methods In this study, three commercial titanium dental implants are grouped by their types into 3 groups (n=10). Each group is divided into 2 subgroups (n=5) according to alkaline treatment. Each experimental specimen is immersed in 5 mL of 5M NaOH solution for 24h at 60°C, then put in an incubator for 24 h to dry at 40°C. All specimens are subjected to surface wettability test through measuring static contact angle (CA) by sessile drop technique and in vitro bioactivity test through immersion into a simulated body fluid (SBF) at 37°C and 7.4p H for 7 days. Then characterized by Scanning Electron Microscope and Energy Dispersive X-ray. Student t-test is used for pair-wise comparisons. The significance level is set at P≤0.05. Results/Conclusions The alkaline surface treatment of Ti dental implants significantly enhances their surface wettability and bioactivity by formation of a porous network structure at a nano scale from sodium titanate hydrogel layer on the surface.
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氢氧化钠碱性处理对一些商业种植体润湿性和生物活性的影响:一项体外研究
目的探讨氢氧化钠(NaOH)碱性处理对部分市售种植体润湿性和生物活性的影响。背景钛种植体的表面对种植体的成功起着重要的作用。润湿性是骨整合的关键表面特性之一。方法将3种市售钛种植体按种植类型分为3组(n=10)。每组按碱处理情况分为2个亚组(n=5)。每个实验标本在5ml的5M NaOH溶液中于60℃下浸泡24h,然后放入培养箱中于40℃下干燥24h。所有样品均通过固滴法测量静接触角(CA)进行表面润湿性测试,并通过在模拟体液(SBF)中37°C、7.4p H浸泡7天进行体外生物活性测试。然后用扫描电镜和能量色散x射线对其进行表征。学生t检验用于两两比较。显著性水平设为P≤0.05。结果/结论钛牙种植体表面碱性处理后,表面钛酸钠水凝胶层在纳米尺度上形成多孔网络结构,显著提高钛牙种植体的表面润湿性和生物活性。
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